hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03898
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SETD2 | Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.43) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) (hSET2) (p231HBP) | UniProt NCBI |
| HNRNPLL | Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) (Stromal RNA-regulating factor) | UniProt NCBI |
| ESRP2 | Epithelial splicing regulatory protein 2 (RNA-binding motif protein 35B) (RNA-binding protein 35B) | UniProt NCBI |
| LIMK2 | LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1) | UniProt NCBI |
| TBX3 | T-box transcription factor TBX3 (T-box protein 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2857 | 0.0271030899343 | 0.4 | SETD2 TBX3 | Mesodermal Commitment Pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HNRNPLL | TBX3 | 0.261 | 0.482 | bioplex (HNRNPLL) bioplex_WMM |
| ESRP2 | HNRNPLL | 0.051 | 0.296 | bioplex (HNRNPLL) bioplex_WMM youn_WMM |
| LIMK2 | HNRNPLL | 0.034 | 0.262 | bioplex (LIMK2) bioplex_WMM youn_WMM |
| SETD2 | HNRNPLL | 0.03 | 0.231 | bioplex (HNRNPLL) bioplex_WMM youn_WMM |
| ESRP2 | TBX3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SETD2 | ESRP2 | 0.008 | 0.045 | bioplex_WMM youn_WMM WMM_only |
| SETD2 | TBX3 | 0.008 | 0.042 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03898 has an average edge precision of 0.208 which is ranked 6070 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SETD2 | HuMAP2_00374 HuMAP2_03898 HuMAP2_05059 HuMAP2_05568 |
| HNRNPLL | HuMAP2_03025 HuMAP2_03898 HuMAP2_05365 HuMAP2_05568 HuMAP2_05797 |
| ESRP2 | HuMAP2_01052 HuMAP2_02586 HuMAP2_03025 HuMAP2_03898 HuMAP2_05365 HuMAP2_05568 |
| LIMK2 | HuMAP2_02337 HuMAP2_03898 HuMAP2_05568 |
| TBX3 | HuMAP2_03025 HuMAP2_03898 HuMAP2_05365 HuMAP2_05568 |