hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03931
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KDM1A | Lysine-specific histone demethylase 1A (EC 1.-.-.-) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) | UniProt NCBI |
| ZC4H2 | Zinc finger C4H2 domain-containing protein (Hepatocellular carcinoma-associated antigen 127) | UniProt NCBI |
| HMG20A | High mobility group protein 20A (HMG box-containing protein 20A) (HMG domain-containing protein 1) (HMG domain-containing protein HMGX1) | UniProt NCBI |
| RCOR3 | REST corepressor 3 | UniProt NCBI |
| PHF14 | PHD finger protein 14 | UniProt NCBI |
| BMP10 | Bone morphogenetic protein 10 (BMP-10) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:626 | 6.43545542379e-07 | 0.5 | RCOR3 KDM1A HMG20A | LSD1 complex |
| CORUM:642 | 0.00113798027977 | 0.333333333333 | RCOR3 KDM1A | CtBP complex |
| HPA:031020_13 | 0.00484174312092 | 0.5 | PHF14 KDM1A HMG20A | ovary; ovarian stroma cells[Supported,High] |
| HPA:013010_13 | 0.00519489721746 | 0.5 | PHF14 KDM1A HMG20A | endometrium 1; cells in endometrial stroma[Supported,High] |
| HPA:031020_03 | 0.00864896230736 | 0.5 | PHF14 KDM1A HMG20A | ovary; ovarian stroma cells[Uncertain,High] |
| HPA:013010_03 | 0.0115832625093 | 0.5 | PHF14 KDM1A HMG20A | endometrium 1; cells in endometrial stroma[Uncertain,High] |
| HPA:050010_13 | 0.0118926812045 | 0.5 | PHF14 KDM1A HMG20A | spleen; cells in red pulp[Supported,High] |
| HPA:043020_13 | 0.0164222898738 | 0.5 | PHF14 KDM1A HMG20A | skin 1; fibroblasts[Supported,High] |
| HPA:007020_13 | 0.0210389711895 | 0.5 | PHF14 KDM1A HMG20A | cerebellum; cells in granular layer[Supported,High] |
| HPA:027020_13 | 0.0259111542195 | 0.5 | PHF14 KDM1A HMG20A | lung; pneumocytes[Supported,High] |
| HPA:050010_03 | 0.0387681239533 | 0.5 | PHF14 KDM1A HMG20A | spleen; cells in red pulp[Uncertain,High] |
| HPA:033010_13 | 0.0433434532907 | 0.5 | PHF14 KDM1A HMG20A | parathyroid gland; glandular cells[Supported,High] |
| CORUM:624 | 0.0499726005494 | 0.166666666667 | KDM1A | LSD1-CoREST complex |
| CORUM:2160 | 0.0499726005494 | 0.166666666667 | KDM1A | AOF2-AR complex |
| CORUM:6477 | 0.0499726005494 | 0.166666666667 | KDM1A | ZEB2-KDM1A complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KDM1A | RCOR3 | 0.997 | 0.93 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction |
| KDM1A | HMG20A | 0.984 | 0.899 | hein_WMM bioplex (HMG20A) bioplex_WMM boldt youn_WMM hein (HMG20A) boldt_WMM |
| HMG20A | RCOR3 | 0.924 | 0.843 | hein_WMM bioplex (HMG20A) bioplex_WMM youn_WMM hein (HMG20A) |
| HMG20A | BMP10 | 0.778 | 0.752 | bioplex (HMG20A) bioplex_WMM |
| PHF14 | HMG20A | 0.569 | 0.655 | hein_WMM bioplex (HMG20A) bioplex_WMM youn_WMM hein (HMG20A) fraction |
| HMG20A | ZC4H2 | 0.559 | 0.65 | bioplex (HMG20A) bioplex_WMM |
| PHF14 | BMP10 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| ZC4H2 | BMP10 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| PHF14 | ZC4H2 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| RCOR3 | BMP10 | 0.008 | 0.024 | bioplex_WMM WMM_only |
| KDM1A | BMP10 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| PHF14 | RCOR3 | 0.008 | 0.024 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| PHF14 | KDM1A | 0.007 | 0.007 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| RCOR3 | ZC4H2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| KDM1A | ZC4H2 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03931 has an average edge precision of 0.335 which is ranked 4170 out of all 6965 complexes.
Related Complexes