hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03935
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KHDRBS3 | KH domain-containing, RNA-binding, signal transduction-associated protein 3 (RNA-binding protein T-Star) (Sam68-like mammalian protein 2) (SLM-2) (Sam68-like phosphotyrosine protein) | UniProt NCBI |
| PA2G4 | Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) (ErbB3-binding protein 1) | UniProt NCBI |
| KHDRBS2 | KH domain-containing, RNA-binding, signal transduction-associated protein 2 (Sam68-like mammalian protein 1) (SLM-1) (hSLM-1) | UniProt NCBI |
| KHDRBS1 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8849468 | 5.40157631853e-09 | 0.75 | KHDRBS2 KHDRBS3 KHDRBS1 | PTK6 Regulates Proteins Involved in RNA Processing |
| REAC:R-HSA-9006927 | 2.0455616978e-05 | 0.75 | KHDRBS2 KHDRBS3 KHDRBS1 | Signaling by Non-Receptor Tyrosine Kinases |
| REAC:R-HSA-8848021 | 2.0455616978e-05 | 0.75 | KHDRBS2 KHDRBS3 KHDRBS1 | Signaling by PTK6 |
| GO:0048024 | 0.0344730150111 | 0.75 | KHDRBS2 KHDRBS3 KHDRBS1 | regulation of mRNA splicing, via spliceosome |
| CORUM:644 | 0.0499140284799 | 0.25 | KHDRBS1 | ASPP1-SAM68 complex |
| CORUM:2578 | 0.0499140284799 | 0.25 | KHDRBS1 | Sam68-p120GAP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KHDRBS3 | KHDRBS2 | 0.686 | 0.712 | bioplex (KHDRBS2) bioplex_WMM |
| KHDRBS1 | KHDRBS2 | 0.296 | 0.496 | bioplex (KHDRBS2) bioplex_WMM gupta_WMM |
| PA2G4 | KHDRBS1 | 0.118 | 0.391 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| PA2G4 | KHDRBS2 | 0.059 | 0.333 | gupta_WMM fraction |
| KHDRBS1 | KHDRBS3 | 0.008 | 0.022 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| PA2G4 | KHDRBS3 | 0.007 | 0.0 | youn_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_03935 has an average edge precision of 0.326 which is ranked 4267 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KHDRBS3 | HuMAP2_01281 HuMAP2_03935 HuMAP2_04377 HuMAP2_05562 |
| PA2G4 | HuMAP2_00601 HuMAP2_03486 HuMAP2_03935 HuMAP2_04085 HuMAP2_04938 |
| KHDRBS2 | HuMAP2_03935 HuMAP2_05562 |
| KHDRBS1 | HuMAP2_00927 HuMAP2_01587 HuMAP2_02395 HuMAP2_03935 HuMAP2_05966 HuMAP2_06616 |