hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03939
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IGF2 | Insulin-like growth factor II (IGF-II) (Somatomedin-A) (T3M-11-derived growth factor) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin] | UniProt NCBI |
| IGFBP1 | Insulin-like growth factor-binding protein 1 (IBP-1) (IGF-binding protein 1) (IGFBP-1) (Placental protein 12) (PP12) | UniProt NCBI |
| PTPN3 | Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-381426 | 0.0350118981581 | 0.666666666667 | IGF2 IGFBP1 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| CORUM:6191 | 0.0499776345577 | 0.333333333333 | IGF2 | IGF2-IGFBP2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IGF2 | IGFBP1 | 0.089 | 0.355 | bioplex (IGFBP1) bioplex_WMM |
| IGFBP1 | PTPN3 | 0.037 | 0.265 | bioplex (IGFBP1) bioplex_WMM |
| IGF2 | PTPN3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_03939 has an average edge precision of 0.238 which is ranked 5556 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IGF2 | HuMAP2_02396 HuMAP2_03939 HuMAP2_04074 HuMAP2_05896 |
| IGFBP1 | HuMAP2_02396 HuMAP2_03939 HuMAP2_04074 HuMAP2_05896 |
| PTPN3 | HuMAP2_02396 HuMAP2_03939 |