hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03946
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CBLL1 | E3 ubiquitin-protein ligase Hakai (EC 2.3.2.27) (Casitas B-lineage lymphoma-transforming sequence-like protein 1) (c-Cbl-like protein 1) (RING finger protein 188) (RING-type E3 ubiquitin transferase Hakai) | UniProt NCBI |
| VIRMA | Protein virilizer homolog | UniProt NCBI |
| ZC3H13 | Zinc finger CCCH domain-containing protein 13 | UniProt NCBI |
| WTAP | Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (hFL(2)D) (WT1-associated protein) (Wilms tumor 1-associating protein) | UniProt NCBI |
| CBLL2 | E3 ubiquitin-protein ligase CBLL2 (EC 2.3.2.27) (Cbl proto-oncogene-like protein 2) (RING-type E3 ubiquitin transferase ZNF645) (Zinc finger protein 645) (c-Cbl-like protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0036396 | 8.53661148134e-09 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | RNA N6-methyladenosine methyltransferase complex |
| GO:0045293 | 8.53661148134e-09 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | mRNA editing complex |
| GO:0080009 | 1.22034183608e-07 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | mRNA methylation |
| GO:0016556 | 4.7240495605e-07 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | mRNA modification |
| CORUM:929 | 1.04649653412e-05 | 0.6 | VIRMA ZC3H13 WTAP | CEN complex |
| GO:0001510 | 7.72519331369e-05 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | RNA methylation |
| GO:0034708 | 0.000625996400903 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | methyltransferase complex |
| GO:0009451 | 0.00125226429768 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | RNA modification |
| GO:0043414 | 0.00896454920435 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | macromolecule methylation |
| GO:0032259 | 0.0120893245383 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | methylation |
| GO:0016607 | 0.0351481133305 | 0.8 | CBLL1 VIRMA ZC3H13 WTAP | nuclear speck |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VIRMA | CBLL2 | 1.0 | 0.949 | bioplex (CBLL2) bioplex_WMM |
| VIRMA | CBLL1 | 0.993 | 0.918 | youn (VIRMA) youn_WMM Malo fraction |
| VIRMA | ZC3H13 | 0.988 | 0.902 | bioplex_WMM Guru youn_WMM Malo fraction |
| CBLL1 | WTAP | 0.976 | 0.889 | youn_WMM Malo fraction |
| CBLL2 | ZC3H13 | 0.96 | 0.865 | bioplex (CBLL2) bioplex_WMM |
| ZC3H13 | WTAP | 0.954 | 0.861 | bioplex_WMM Guru youn_WMM Malo fraction |
| VIRMA | WTAP | 0.921 | 0.843 | hein_WMM youn (VIRMA) bioplex_WMM Guru youn_WMM Malo fraction |
| CBLL2 | WTAP | 0.627 | 0.68 | bioplex (CBLL2) bioplex_WMM |
| CBLL1 | ZC3H13 | 0.008 | 0.023 | hein_WMM WMM_only |
Images
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Complex HuMAP2_03946 has an average edge precision of 0.77 which is ranked 1052 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CBLL1 | HuMAP2_00310 HuMAP2_03946 HuMAP2_05045 HuMAP2_05108 |
| VIRMA | HuMAP2_00310 HuMAP2_03946 HuMAP2_05045 HuMAP2_05108 |
| ZC3H13 | HuMAP2_00310 HuMAP2_03946 HuMAP2_05045 HuMAP2_05108 |
| WTAP | HuMAP2_00310 HuMAP2_03946 HuMAP2_05045 HuMAP2_05108 |
| CBLL2 | HuMAP2_00310 HuMAP2_03946 HuMAP2_05045 HuMAP2_05108 |