hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_03979
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LDHAL6A | L-lactate dehydrogenase A-like 6A (EC 1.1.1.27) | UniProt NCBI |
| RPN1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1) | UniProt NCBI |
| SUCLG2 | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial (EC 6.2.1.4) (GTP-specific succinyl-CoA synthetase subunit beta) (G-SCS) (GTPSCS) (Succinyl-CoA synthetase beta-G chain) (SCS-betaG) | UniProt NCBI |
| CANX | Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90) | UniProt NCBI |
| UQCRC2 | Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6131 | 0.000301566439547 | 0.4 | CANX RPN1 | SELK multiprotein complex |
| REAC:R-HSA-1428517 | 0.00196642775139 | 0.6 | UQCRC2 LDHAL6A SUCLG2 | The citric acid (TCA) cycle and respiratory electron transport |
| KEGG:00640 | 0.00239834964959 | 0.4 | LDHAL6A SUCLG2 | Propanoate metabolism |
| KEGG:01100 | 0.0121945453342 | 0.8 | UQCRC2 SUCLG2 LDHAL6A RPN1 | Metabolic pathways |
| REAC:R-HSA-71406 | 0.017778070678 | 0.4 | LDHAL6A SUCLG2 | Pyruvate metabolism and Citric Acid (TCA) cycle |
| CORUM:393 | 0.0499494897235 | 0.2 | SUCLG2 | Succinyl-CoA synthetase, GDP-forming |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPN1 | UQCRC2 | 0.28 | 0.486 | bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| LDHAL6A | SUCLG2 | 0.162 | 0.42 | Guru fraction |
| RPN1 | SUCLG2 | 0.152 | 0.411 | bioplex (SUCLG2) bioplex_WMM Guru fraction |
| RPN1 | CANX | 0.109 | 0.378 | bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| CANX | UQCRC2 | 0.05 | 0.297 | bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| CANX | SUCLG2 | 0.007 | 0.001 | bioplex (SUCLG2) bioplex_WMM |
| UQCRC2 | SUCLG2 | 0.005 | 0.008 | bioplex (SUCLG2) bioplex_WMM |
Images
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Complex HuMAP2_03979 has an average edge precision of 0.286 which is ranked 4801 out of all 6965 complexes.
Related Complexes