hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_03990
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NLRP4 | NACHT, LRR and PYD domains-containing protein 4 (Cancer/testis antigen 58) (CT58) (PAAD and NACHT-containing protein 2) (PAN2) (PYRIN and NACHT-containing protein 2) (PYRIN-containing APAF1-like protein 4) (PYPAF4) (Ribonuclease inhibitor 2) | UniProt NCBI |
| YTHDF1 | YTH domain-containing family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1) | UniProt NCBI |
| YTHDF2 | YTH domain-containing family protein 2 (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2) | UniProt NCBI |
| YTHDF3 | YTH domain-containing family protein 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1990247 | 2.03382379613e-05 | 0.75 | YTHDF3 YTHDF1 YTHDF2 | N6-methyladenosine-containing RNA binding |
| GO:0045948 | 0.00064271072446 | 0.75 | YTHDF3 YTHDF1 YTHDF2 | positive regulation of translational initiation |
| GO:0006446 | 0.0165706850483 | 0.75 | YTHDF3 YTHDF1 YTHDF2 | regulation of translational initiation |
| GO:0045727 | 0.0439367749778 | 0.75 | YTHDF3 YTHDF1 YTHDF2 | positive regulation of translation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| YTHDF1 | YTHDF3 | 0.669 | 0.702 | hein_WMM youn (YTHDF1,YTHDF3) bioplex (YTHDF1,YTHDF3) bioplex_WMM youn_WMM gupta_WMM |
| YTHDF2 | YTHDF3 | 0.027 | 0.223 | hein_WMM youn (YTHDF2,YTHDF3) bioplex (YTHDF3) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| YTHDF1 | NLRP4 | 0.024 | 0.21 | youn (YTHDF1) youn_WMM fraction |
| YTHDF2 | YTHDF1 | 0.021 | 0.185 | hein_WMM youn (YTHDF1,YTHDF2) bioplex (YTHDF1) bioplex_WMM youn_WMM gupta_WMM |
| YTHDF2 | NLRP4 | 0.007 | 0.005 | youn (YTHDF2) youn_WMM |
| YTHDF3 | NLRP4 | 0.007 | 0.009 | youn (YTHDF3) youn_WMM |
Images
Click to enlarge
Complex HuMAP2_03990 has an average edge precision of 0.222 which is ranked 5819 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NLRP4 | HuMAP2_03990 |
| YTHDF1 | HuMAP2_02210 HuMAP2_02912 HuMAP2_03990 HuMAP2_05788 |
| YTHDF2 | HuMAP2_00102 HuMAP2_02493 HuMAP2_03990 HuMAP2_05997 |
| YTHDF3 | HuMAP2_02210 HuMAP2_03990 HuMAP2_05788 |