hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04006
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CYC1 | Cytochrome c1, heme protein, mitochondrial (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1) | UniProt NCBI |
| UQCRH | Cytochrome b-c1 complex subunit 6, mitochondrial (Complex III subunit 6) (Complex III subunit VIII) (Cytochrome c1 non-heme 11 kDa protein) (Mitochondrial hinge protein) (Ubiquinol-cytochrome c reductase complex 11 kDa protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04260 | 0.000415808000786 | 1.0 | CYC1 UQCRH | Cardiac muscle contraction |
| KEGG:00190 | 0.00100713074717 | 1.0 | CYC1 UQCRH | Oxidative phosphorylation |
| KEGG:05012 | 0.00114894316007 | 1.0 | CYC1 UQCRH | Parkinson disease |
| KEGG:04932 | 0.00128068864242 | 1.0 | CYC1 UQCRH | Non-alcoholic fatty liver disease (NAFLD) |
| KEGG:05010 | 0.00171881896746 | 1.0 | CYC1 UQCRH | Alzheimer disease |
| KEGG:05016 | 0.00224682217969 | 1.0 | CYC1 UQCRH | Huntington disease |
| KEGG:04714 | 0.00317122901933 | 1.0 | CYC1 UQCRH | Thermogenesis |
| WP:WP4396 | 0.00347096768628 | 1.0 | CYC1 UQCRH | Nonalcoholic fatty liver disease |
| REAC:R-HSA-611105 | 0.00732546145404 | 1.0 | CYC1 UQCRH | Respiratory electron transport |
| REAC:R-HSA-163200 | 0.011178409494 | 1.0 | CYC1 UQCRH | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| REAC:R-HSA-1428517 | 0.0226752444459 | 1.0 | CYC1 UQCRH | The citric acid (TCA) cycle and respiratory electron transport |
| GO:0005750 | 0.0247952876258 | 1.0 | CYC1 UQCRH | mitochondrial respiratory chain complex III |
| GO:0045275 | 0.0247952876258 | 1.0 | CYC1 UQCRH | respiratory chain complex III |
| GO:0006122 | 0.0247952876258 | 1.0 | CYC1 UQCRH | mitochondrial electron transport, ubiquinol to cytochrome c |
| HPA:021010_13 | 0.0324969938972 | 1.0 | CYC1 UQCRH | heart muscle; myocytes[Supported,High] |
| HPA:040010_13 | 0.0474420413729 | 1.0 | CYC1 UQCRH | seminal vesicle; glandular cells[Supported,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CYC1 | UQCRH | 0.937 | 0.85 | bioplex (CYC1,UQCRH) bioplex_WMM boldt fraction boldt_WMM |
Images
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Complex HuMAP2_04006 has an average edge precision of 0.85 which is ranked 761 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CYC1 | HuMAP2_04006 HuMAP2_04147 HuMAP2_05043 |
| UQCRH | HuMAP2_04006 HuMAP2_04147 HuMAP2_05043 |