hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04010
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MICALL1 | MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13) | UniProt NCBI |
| MDC1 | Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1) | UniProt NCBI |
| SH3KBP1 | SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1) | UniProt NCBI |
| STAP1 | Signal-transducing adaptor protein 1 (STAP-1) (BCR downstream-signaling protein 1) (Docking protein BRDG1) (Stem cell adaptor protein 1) | UniProt NCBI |
| RTKN2 | Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1) | UniProt NCBI |
| CD2AP | CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:846 | 0.000176032589326 | 0.333333333333 | CD2AP SH3KBP1 | RICH1/AMOT polarity complex, Flag-Rich1 precipitated |
| CORUM:3173 | 0.0249904952816 | 0.166666666667 | SH3KBP1 | CIN85 homotetramer complex |
| CORUM:3174 | 0.0249904952816 | 0.166666666667 | SH3KBP1 | CIN85-BLNK complex |
| CORUM:2455 | 0.0499726005494 | 0.166666666667 | SH3KBP1 | CIN85-SH3GL2 complex |
| CORUM:2457 | 0.0499726005494 | 0.166666666667 | SH3KBP1 | CIN85-SH3GL3 complex |
| CORUM:3175 | 0.0499726005494 | 0.166666666667 | SH3KBP1 | CIN85-CBL complex |
| CORUM:5720 | 0.0499726005494 | 0.166666666667 | SH3KBP1 | CIN85-CBL complex |
| CORUM:6293 | 0.0499726005494 | 0.166666666667 | SH3KBP1 | DDN-MAGI2-SH3KBP1 complex |
| CORUM:7333 | 0.0499726005494 | 0.166666666667 | MICALL1 | MICALL1-RAB13 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SH3KBP1 | STAP1 | 0.998 | 0.943 | bioplex (STAP1) bioplex_WMM |
| SH3KBP1 | RTKN2 | 0.936 | 0.85 | bioplex (SH3KBP1) bioplex_WMM |
| MDC1 | SH3KBP1 | 0.933 | 0.848 | bioplex (SH3KBP1) bioplex_WMM youn_WMM gupta_WMM |
| SH3KBP1 | CD2AP | 0.924 | 0.844 | hein_WMM bioplex (SH3KBP1) bioplex_WMM youn_WMM hein (CD2AP) gupta_WMM |
| SH3KBP1 | MICALL1 | 0.896 | 0.821 | bioplex (SH3KBP1) bioplex_WMM youn_WMM gupta_WMM |
| STAP1 | CD2AP | 0.506 | 0.626 | bioplex (STAP1) bioplex_WMM |
| MDC1 | MICALL1 | 0.009 | 0.099 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MDC1 | RTKN2 | 0.008 | 0.094 | bioplex_WMM youn_WMM WMM_only |
| MDC1 | CD2AP | 0.008 | 0.083 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MICALL1 | RTKN2 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| MICALL1 | CD2AP | 0.008 | 0.012 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| RTKN2 | CD2AP | 0.007 | 0.008 | bioplex_WMM youn_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_04010 has an average edge precision of 0.443 which is ranked 2921 out of all 6965 complexes.
Related Complexes