hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04028
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NOP58 | Nucleolar protein 58 (Nucleolar protein 5) | UniProt NCBI |
| BTF3 | Transcription factor BTF3 (Nascent polypeptide-associated complex subunit beta) (NAC-beta) (RNA polymerase B transcription factor 3) | UniProt NCBI |
| KPNB1 | Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97) | UniProt NCBI |
| SYAP1 | Synapse-associated protein 1 (BSD domain-containing signal transducer and Akt interactor protein) (BSTA) | UniProt NCBI |
| EIF3B | Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116) | UniProt NCBI |
| NACA2 | Nascent polypeptide-associated complex subunit alpha-2 (Alpha-NAC-like) (Hom s 2.01) (Nascent polypeptide-associated complex subunit alpha-like) (NAC-alpha-like) | UniProt NCBI |
| BTF3L4 | Transcription factor BTF3 homolog 4 (Basic transcription factor 3-like 4) | UniProt NCBI |
| MYH13 | Myosin-13 (Myosin heavy chain 13) (Myosin heavy chain, skeletal muscle, extraocular) (MyHC-EO) (Myosin heavy chain, skeletal muscle, laryngeal) (MyHC-IIL) (Superfast myosin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6142 | 0.0497224828424 | 0.125 | KPNB1 | KPNA2-KPNB1 complex |
| CORUM:6143 | 0.0497224828424 | 0.125 | KPNB1 | KPNB1-RAN complex |
| CORUM:7296 | 0.0497224828424 | 0.125 | EIF3B | PRT1-RGP1 complex |
| CORUM:7543 | 0.0497224828424 | 0.125 | KPNB1 | KPNB1-SMN-SPN complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NACA2 | BTF3 | 1.0 | 0.949 | Guru fraction |
| NACA2 | BTF3L4 | 1.0 | 0.949 | Guru fraction |
| NOP58 | BTF3 | 0.488 | 0.616 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| EIF3B | NOP58 | 0.182 | 0.437 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| KPNB1 | BTF3 | 0.16 | 0.418 | bioplex_WMM fraction treiber_WMM |
| NOP58 | NACA2 | 0.128 | 0.399 | fraction |
| SYAP1 | NACA2 | 0.093 | 0.355 | fraction |
| NOP58 | BTF3L4 | 0.071 | 0.353 | youn_WMM gupta_WMM fraction |
| KPNB1 | NACA2 | 0.071 | 0.353 | fraction |
| EIF3B | NACA2 | 0.061 | 0.339 | fraction |
| NACA2 | MYH13 | 0.052 | 0.299 | fraction |
| KPNB1 | NOP58 | 0.046 | 0.294 | bioplex_WMM fraction treiber_WMM |
| SYAP1 | BTF3 | 0.038 | 0.266 | bioplex (SYAP1) bioplex_WMM youn_WMM gupta_WMM fraction |
| SYAP1 | BTF3L4 | 0.009 | 0.105 | bioplex_WMM youn_WMM gupta_WMM fraction |
| EIF3B | SYAP1 | 0.008 | 0.013 | youn_WMM gupta_WMM WMM_only |
| NOP58 | SYAP1 | 0.007 | 0.011 | youn_WMM gupta_WMM WMM_only |
| EIF3B | BTF3 | 0.003 | 0.013 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| KPNB1 | BTF3L4 | 0.003 | 0.017 | fraction |
| KPNB1 | SYAP1 | 0.0 | 0.008 | bioplex (SYAP1) bioplex_WMM fraction |
| EIF3B | BTF3L4 | 0.0 | 0.008 | hein_WMM youn_WMM gupta_WMM fraction |
| BTF3 | BTF3L4 | 0.0 | 0.0 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
| EIF3B | KPNB1 | 0.0 | 0.001 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_04028 has an average edge precision of 0.282 which is ranked 4856 out of all 6965 complexes.
Related Complexes