hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04033
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RUVBL2 | RuvB-like 2 (EC 3.6.4.12) (48 kDa TATA box-binding protein-interacting protein) (48 kDa TBP-interacting protein) (51 kDa erythrocyte cytosolic protein) (ECP-51) (INO80 complex subunit J) (Repressing pontin 52) (Reptin 52) (TIP49b) (TIP60-associated protein 54-beta) (TAP54-beta) | UniProt NCBI |
| RUVBL1 | RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1173 | 5.02777038712e-06 | 1.0 | RUVBL1 RUVBL2 | TIP49-TIP48-BAF53 complex |
| CORUM:1171 | 1.67592346237e-05 | 1.0 | RUVBL1 RUVBL2 | c-MYC-ATPase-helicase complex |
| CORUM:1170 | 1.67592346237e-05 | 1.0 | RUVBL1 RUVBL2 | c-MYC-ATPase-helicase complex |
| CORUM:525 | 1.67592346237e-05 | 1.0 | RUVBL1 RUVBL2 | TIP60 histone acetylase complex |
| CORUM:1166 | 2.51388519356e-05 | 1.0 | RUVBL1 RUVBL2 | p400-associated complex |
| REAC:R-HSA-171319 | 2.51388519356e-05 | 1.0 | RUVBL1 RUVBL2 | Telomere Extension By Telomerase |
| CORUM:787 | 4.69258569465e-05 | 1.0 | RUVBL1 RUVBL2 | NuA4/Tip60-HAT complex B |
| CORUM:781 | 6.03332446455e-05 | 1.0 | RUVBL1 RUVBL2 | URI complex (Unconventional prefoldin RPB5 Interactor) |
| CORUM:799 | 7.54165558069e-05 | 1.0 | RUVBL1 RUVBL2 | DMAP1-associated complex |
| CORUM:304 | 7.54165558069e-05 | 1.0 | RUVBL1 RUVBL2 | SRCAP-associated chromatin remodeling complex |
| CORUM:302 | 0.000130722030065 | 1.0 | RUVBL1 RUVBL2 | INO80 chromatin remodeling complex |
| CORUM:2857 | 0.000152509035076 | 1.0 | RUVBL1 RUVBL2 | NuA4/Tip60 HAT complex |
| CORUM:528 | 0.000175971963549 | 1.0 | RUVBL1 RUVBL2 | NuA4/Tip60-HAT complex |
| CORUM:798 | 0.000175971963549 | 1.0 | RUVBL1 RUVBL2 | NuA4/Tip60-HAT complex A |
| CORUM:529 | 0.000201110815485 | 1.0 | RUVBL1 RUVBL2 | NuA4/Tip60-HAT complex |
| REAC:R-HSA-180786 | 0.000729026706133 | 1.0 | RUVBL1 RUVBL2 | Extension of Telomeres |
| GO:0097255 | 0.00450823411379 | 1.0 | RUVBL1 RUVBL2 | R2TP complex |
| REAC:R-HSA-157579 | 0.00542999201809 | 1.0 | RUVBL1 RUVBL2 | Telomere Maintenance |
| REAC:R-HSA-73886 | 0.0096834857656 | 1.0 | RUVBL1 RUVBL2 | Chromosome Maintenance |
| GO:0000492 | 0.0126230555186 | 1.0 | RUVBL1 RUVBL2 | box C/D snoRNP assembly |
| REAC:R-HSA-3214847 | 0.0167776697818 | 1.0 | RUVBL1 RUVBL2 | HATs acetylate histones |
| GO:0000491 | 0.020287053512 | 1.0 | RUVBL1 RUVBL2 | small nucleolar ribonucleoprotein complex assembly |
| GO:0000812 | 0.029754345151 | 1.0 | RUVBL1 RUVBL2 | Swr1 complex |
| GO:1904874 | 0.0473364581948 | 1.0 | RUVBL1 RUVBL2 | positive regulation of telomerase RNA localization to Cajal body |
| GO:0033202 | 0.0473364581948 | 1.0 | RUVBL1 RUVBL2 | DNA helicase complex |
| GO:0031011 | 0.0473364581948 | 1.0 | RUVBL1 RUVBL2 | Ino80 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RUVBL2 | RUVBL1 | 1.0 | 0.949 | hein_WMM bioplex (RUVBL1,RUVBL2) bioplex_WMM Guru boldt hein (RUVBL1,RUVBL2) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_04033 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RUVBL2 | HuMAP2_00294 HuMAP2_01310 HuMAP2_01377 HuMAP2_04033 HuMAP2_04912 HuMAP2_06035 |
| RUVBL1 | HuMAP2_01310 HuMAP2_01377 HuMAP2_04033 HuMAP2_04912 HuMAP2_06035 |