hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04043
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PLEKHB1 | Pleckstrin homology domain-containing family B member 1 (PH domain-containing family B member 1) (Evectin-1) (PH domain-containing protein in retina 1) (PHRET1) (Pleckstrin homology domain retinal protein 1) | UniProt NCBI |
| DIRAS1 | GTP-binding protein Di-Ras1 (Distinct subgroup of the Ras family member 1) (Ras-related inhibitor of cell growth) (Rig) (Small GTP-binding tumor suppressor 1) | UniProt NCBI |
| RAP1A | Ras-related protein Rap-1A (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1) | UniProt NCBI |
| DIRAS2 | GTP-binding protein Di-Ras2 (Distinct subgroup of the Ras family member 2) | UniProt NCBI |
| RAP1GDS1 | Rap1 GTPase-GDP dissociation stimulator 1 (Exchange factor smgGDS) (SMG GDS protein) (SMG P21 stimulatory GDP/GTP exchange protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0019003 | 0.0358473364726 | 0.6 | DIRAS1 DIRAS2 RAP1A | GDP binding |
| CORUM:2256 | 0.0499494897235 | 0.2 | RAP1A | RIAM-Rap1-GTP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DIRAS1 | RAP1GDS1 | 0.523 | 0.633 | bioplex (RAP1GDS1) bioplex_WMM |
| DIRAS2 | RAP1GDS1 | 0.213 | 0.463 | bioplex (DIRAS2) bioplex_WMM |
| RAP1A | RAP1GDS1 | 0.194 | 0.448 | bioplex (RAP1GDS1) bioplex_WMM |
| PLEKHB1 | RAP1GDS1 | 0.175 | 0.434 | bioplex (RAP1GDS1) bioplex_WMM |
| PLEKHB1 | DIRAS1 | 0.009 | 0.09 | bioplex_WMM WMM_only |
| PLEKHB1 | RAP1A | 0.008 | 0.011 | bioplex_WMM WMM_only |
| RAP1A | DIRAS1 | 0.007 | 0.008 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04043 has an average edge precision of 0.298 which is ranked 4624 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PLEKHB1 | HuMAP2_00002 HuMAP2_02283 HuMAP2_03541 HuMAP2_04035 HuMAP2_04043 HuMAP2_04289 |
| DIRAS1 | HuMAP2_03409 HuMAP2_03460 HuMAP2_03541 HuMAP2_04035 HuMAP2_04043 |
| RAP1A | HuMAP2_00677 HuMAP2_03409 HuMAP2_03541 HuMAP2_04035 HuMAP2_04043 |
| DIRAS2 | HuMAP2_01880 HuMAP2_03409 HuMAP2_03541 HuMAP2_04035 HuMAP2_04043 |
| RAP1GDS1 | HuMAP2_03409 HuMAP2_03460 HuMAP2_03541 HuMAP2_04035 HuMAP2_04043 |