hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04053
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CETN2 | Centrin-2 (Caltractin isoform 1) | UniProt NCBI |
| HIST1H2BO | Histone H2B type 1-O (Histone H2B.2) (Histone H2B.n) (H2B/n) | UniProt NCBI |
| XPC | DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125) | UniProt NCBI |
| CETN3 | Centrin-3 | UniProt NCBI |
| DNAH14 | Dynein heavy chain 14, axonemal (Axonemal beta dynein heavy chain 14) (Ciliary dynein heavy chain 14) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03420 | 0.00403884103568 | 0.4 | XPC CETN2 | Nucleotide excision repair |
| REAC:R-HSA-5696394 | 0.00944309181669 | 0.4 | XPC CETN2 | DNA Damage Recognition in GG-NER |
| REAC:R-HSA-5696395 | 0.012121451174 | 0.4 | XPC CETN2 | Formation of Incision Complex in GG-NER |
| GO:0071942 | 0.0135228859698 | 0.4 | XPC CETN2 | XPC complex |
| REAC:R-HSA-73894 | 0.0143782387474 | 0.6 | XPC CETN2 HIST1H2BO | DNA Repair |
| REAC:R-HSA-3108214 | 0.0332320424718 | 0.4 | XPC CETN2 | SUMOylation of DNA damage response and repair proteins |
| GO:0070390 | 0.0450641792523 | 0.4 | CETN2 CETN3 | transcription export complex 2 |
| REAC:R-HSA-5696399 | 0.0465369402216 | 0.4 | XPC CETN2 | Global Genome Nucleotide Excision Repair (GG-NER) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| XPC | CETN2 | 0.818 | 0.773 | hein_WMM bioplex (XPC) bioplex_WMM hein (CETN2) gupta (CETN2) |
| HIST1H2BO | XPC | 0.182 | 0.438 | bioplex (XPC) bioplex_WMM |
| CETN2 | CETN3 | 0.104 | 0.37 | hein_WMM bioplex_WMM hein (CETN2) gupta_WMM |
| XPC | CETN3 | 0.051 | 0.3 | hein_WMM bioplex (XPC) bioplex_WMM |
| CETN2 | DNAH14 | 0.026 | 0.216 | bioplex (DNAH14) bioplex_WMM |
| HIST1H2BO | CETN2 | 0.009 | 0.093 | bioplex_WMM WMM_only |
| HIST1H2BO | CETN3 | 0.007 | 0.004 | bioplex_WMM youn_WMM WMM_only |
| HIST1H2BO | DNAH14 | 0.007 | 0.001 | youn_WMM WMM_only |
| XPC | DNAH14 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| CETN3 | DNAH14 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04053 has an average edge precision of 0.22 which is ranked 5858 out of all 6965 complexes.
Related Complexes