hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04064
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ST13 | Hsc70-interacting protein (Hip) (Aging-associated protein 2) (Progesterone receptor-associated p48 protein) (Protein FAM10A1) (Putative tumor suppressor ST13) (Renal carcinoma antigen NY-REN-33) (Suppression of tumorigenicity 13 protein) | UniProt NCBI |
| THG1L | Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase) | UniProt NCBI |
| PACSIN1 | Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1) | UniProt NCBI |
| COBL | Protein cordon-bleu | UniProt NCBI |
| COBLL1 | Cordon-bleu protein-like 1 | UniProt NCBI |
| PACSIN2 | Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) | UniProt NCBI |
| PACSIN3 | Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0097320 | 0.00258594907681 | 0.428571428571 | PACSIN2 PACSIN1 PACSIN3 | plasma membrane tubulation |
| REAC:R-HSA-8856828 | 0.00362218339674 | 0.428571428571 | PACSIN2 PACSIN1 PACSIN3 | Clathrin-mediated endocytosis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PACSIN2 | COBLL1 | 1.0 | 0.949 | bioplex (PACSIN2) bioplex_WMM gupta_WMM |
| COBLL1 | PACSIN3 | 0.993 | 0.916 | hein_WMM bioplex (PACSIN3) bioplex_WMM hein (COBLL1) |
| PACSIN1 | COBLL1 | 0.992 | 0.914 | bioplex (PACSIN1) bioplex_WMM |
| ST13 | PACSIN3 | 0.938 | 0.85 | Guru fraction |
| PACSIN2 | ST13 | 0.915 | 0.839 | bioplex_WMM Guru youn_WMM fraction treiber_WMM |
| THG1L | PACSIN2 | 0.589 | 0.663 | bioplex (PACSIN2) bioplex_WMM |
| PACSIN2 | COBL | 0.15 | 0.41 | bioplex (COBL,PACSIN2) bioplex_WMM fraction |
| PACSIN2 | PACSIN1 | 0.114 | 0.384 | bioplex (PACSIN1) bioplex_WMM fraction |
| PACSIN3 | COBL | 0.106 | 0.373 | hein_WMM bioplex (COBL,PACSIN3) bioplex_WMM |
| PACSIN1 | COBL | 0.079 | 0.352 | bioplex (PACSIN1) bioplex_WMM fraction |
| PACSIN2 | PACSIN3 | 0.076 | 0.358 | bioplex (PACSIN2,PACSIN3) bioplex_WMM |
| COBLL1 | COBL | 0.013 | 0.144 | bioplex_WMM WMM_only |
| PACSIN1 | PACSIN3 | 0.009 | 0.113 | bioplex (PACSIN1) bioplex_WMM |
| THG1L | COBLL1 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| THG1L | PACSIN3 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| THG1L | COBL | 0.008 | 0.079 | bioplex_WMM WMM_only |
| ST13 | COBL | 0.0 | 0.012 | fraction |
Images
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Complex HuMAP2_04064 has an average edge precision of 0.443 which is ranked 2922 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ST13 | HuMAP2_04064 HuMAP2_06698 |
| THG1L | HuMAP2_00146 HuMAP2_02117 HuMAP2_02460 HuMAP2_03505 HuMAP2_04064 HuMAP2_04237 |
| PACSIN1 | HuMAP2_03007 HuMAP2_04064 |
| COBL | HuMAP2_04064 HuMAP2_06256 |
| COBLL1 | HuMAP2_03007 HuMAP2_04064 |
| PACSIN2 | HuMAP2_02117 HuMAP2_04064 |
| PACSIN3 | HuMAP2_04064 HuMAP2_06698 |