hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04123
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TERF2IP | Telomeric repeat-binding factor 2-interacting protein 1 (TERF2-interacting telomeric protein 1) (TRF2-interacting telomeric protein 1) (Dopamine receptor-interacting protein 5) (Repressor/activator protein 1 homolog) (RAP1 homolog) (hRap1) | UniProt NCBI |
| SUPT20H | Transcription factor SPT20 homolog (p38-interacting protein) (p38IP) | UniProt NCBI |
| TADA3 | Transcriptional adapter 3 (ADA3 homolog) (hADA3) (STAF54) (Transcriptional adapter 3-like) (ADA3-like protein) | UniProt NCBI |
| TERF2 | Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein) | UniProt NCBI |
| SUPT7L | STAGA complex 65 subunit gamma (Adenocarcinoma antigen ART1) (SPTF-associated factor 65 gamma) (STAF65gamma) (Suppressor of Ty 7-like) | UniProt NCBI |
| TADA1 | Transcriptional adapter 1 (SPT3-associated factor 42) (STAF42) (Transcriptional adapter 1-like protein) | UniProt NCBI |
| SGF29 | SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29) | UniProt NCBI |
| TADA2B | Transcriptional adapter 2-beta (ADA2-like protein beta) (ADA2-beta) | UniProt NCBI |
| TAF5L | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (PCAF-associated factor 65 beta) (PAF65-beta) | UniProt NCBI |
| SUPT3H | Transcription initiation protein SPT3 homolog (SPT3-like protein) | UniProt NCBI |
| TAF6L | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65-alpha) (PAF65-alpha) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6664 | 1.82280922675e-24 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | STAGA complex, SPT3-linked |
| CORUM:6643 | 1.40481161738e-20 | 0.727272727273 | TADA2B TAF6L SGF29 SUPT20H TADA3 SUPT7L TAF5L SUPT3H | SAGA complex, GCN5-linked |
| GO:0070461 | 5.65543274378e-20 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | SAGA-type complex |
| CORUM:476 | 1.90366725071e-15 | 0.545454545455 | TAF6L SUPT3H TADA1 SUPT7L TAF5L TADA3 | STAGA complex |
| CORUM:475 | 1.90366725071e-15 | 0.545454545455 | TAF6L SUPT3H TADA1 SUPT7L TAF5L TADA3 | STAGA complex |
| GO:0000123 | 5.01594501148e-15 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | histone acetyltransferase complex |
| REAC:R-HSA-3214847 | 5.97805620303e-15 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | HATs acetylate histones |
| GO:1902493 | 1.56959325735e-14 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | acetyltransferase complex |
| GO:0031248 | 1.56959325735e-14 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | protein acetyltransferase complex |
| GO:0030914 | 7.03607645669e-13 | 0.545454545455 | TAF6L SUPT3H TADA1 SUPT7L TAF5L TADA3 | STAGA complex |
| GO:0006473 | 1.87667768274e-12 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TERF2IP TAF5L TADA3 | protein acetylation |
| REAC:R-HSA-4839726 | 2.09223518187e-12 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | Chromatin organization |
| REAC:R-HSA-3247509 | 2.09223518187e-12 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | Chromatin modifying enzymes |
| GO:0043543 | 1.34126920332e-11 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TERF2IP TAF5L TADA3 | protein acylation |
| GO:0016573 | 4.40682624074e-11 | 0.727272727273 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TAF5L TADA3 | histone acetylation |
| GO:0043966 | 5.06464425371e-11 | 0.636363636364 | TAF6L SGF29 SUPT3H TADA1 SUPT7L TAF5L TADA3 | histone H3 acetylation |
| GO:0018393 | 5.13450152913e-11 | 0.727272727273 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TAF5L TADA3 | internal peptidyl-lysine acetylation |
| GO:0006475 | 7.43118359937e-11 | 0.727272727273 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TAF5L TADA3 | internal protein amino acid acetylation |
| GO:0018394 | 7.98534648201e-11 | 0.727272727273 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TAF5L TADA3 | peptidyl-lysine acetylation |
| GO:0004402 | 1.17427644664e-10 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | histone acetyltransferase activity |
| GO:0061733 | 1.52169711847e-10 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | peptide-lysine-N-acetyltransferase activity |
| GO:0034212 | 4.39191508965e-10 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | peptide N-acetyltransferase activity |
| GO:0008080 | 1.21161860265e-09 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | N-acetyltransferase activity |
| CORUM:471 | 2.28254486498e-09 | 0.363636363636 | TAF5L TAF6L TADA3 SUPT3H | PCAF complex |
| CORUM:477 | 2.28254486498e-09 | 0.363636363636 | TAF5L TAF6L TADA3 SUPT3H | PCAF complex |
| GO:0044451 | 2.3325386199e-09 | 1.0 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TERF2 TADA1 TERF2IP TAF5L TADA3 | nucleoplasm part |
| GO:0016410 | 3.75277774579e-09 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | N-acyltransferase activity |
| GO:0016407 | 5.97837929261e-09 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | acetyltransferase activity |
| CORUM:462 | 1.4808654147e-08 | 0.363636363636 | TAF5L TAF6L TADA3 SUPT3H | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:445 | 1.4808654147e-08 | 0.363636363636 | TAF5L TAF6L TADA3 SUPT3H | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:456 | 1.4808654147e-08 | 0.363636363636 | TAF5L TAF6L TADA3 SUPT3H | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:455 | 1.4808654147e-08 | 0.363636363636 | TAF5L TAF6L TADA3 SUPT3H | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:470 | 1.97374430295e-08 | 0.363636363636 | TAF5L TAF6L TADA3 SUPT3H | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| CORUM:513 | 1.97374430295e-08 | 0.363636363636 | TAF5L TAF6L TADA3 SUPT3H | TFTC complex (TATA-binding protein-free TAF-II-containing complex) |
| GO:0018205 | 1.31645704034e-07 | 0.727272727273 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TAF5L TADA3 | peptidyl-lysine modification |
| GO:0016570 | 3.67828290332e-07 | 0.727272727273 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TAF5L TADA3 | histone modification |
| GO:0051276 | 4.37370436123e-07 | 0.909090909091 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TERF2 TADA1 TERF2IP TAF5L TADA3 | chromosome organization |
| GO:0016569 | 5.28318758427e-07 | 0.727272727273 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TAF5L TADA3 | covalent chromatin modification |
| GO:0016747 | 6.20036293499e-07 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | transferase activity, transferring acyl groups other than amino-acyl groups |
| GO:0016746 | 1.42476786232e-06 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | transferase activity, transferring acyl groups |
| CORUM:438 | 2.42644341986e-06 | 0.272727272727 | TAF5L TADA3 SUPT3H | GCN5-TRRAP histone acetyltransferase complex |
| GO:0000124 | 2.64968960261e-06 | 0.363636363636 | SUPT20H TADA3 TADA1 SGF29 | SAGA complex |
| GO:1990234 | 2.65527121969e-06 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | transferase complex |
| CORUM:0000000 | 6.27334655689e-06 | 1.0 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TERF2 TADA1 TERF2IP TAF5L TADA3 | CORUM root |
| GO:0003713 | 1.10511844297e-05 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | transcription coactivator activity |
| GO:0018193 | 1.98026850639e-05 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TERF2IP TAF5L TADA3 | peptidyl-amino acid modification |
| CORUM:1205 | 3.35524866385e-05 | 0.181818181818 | TERF2IP TERF2 | TRF2-Rap1 complex III |
| GO:0006325 | 3.85617892229e-05 | 0.727272727273 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TADA1 TAF5L TADA3 | chromatin organization |
| CORUM:1207 | 0.000201152732593 | 0.181818181818 | TERF2IP TERF2 | TRF2-Rap1 complex II |
| GO:1902494 | 0.00031759147892 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TADA1 TAF5L TADA3 | catalytic complex |
| GO:0003712 | 0.000460742706642 | 0.636363636364 | TADA2B TAF6L TADA3 TADA1 SUPT7L TAF5L SUPT3H | transcription coregulator activity |
| CORUM:1197 | 0.00050247669008 | 0.181818181818 | TERF2IP TERF2 | Telomere-associated protein complex |
| CORUM:138 | 0.00050247669008 | 0.181818181818 | TERF2IP TERF2 | Telomere-associated protein complex |
| CORUM:1206 | 0.00050247669008 | 0.181818181818 | TERF2IP TERF2 | TRF-Rap1 complex I, 2MD |
| GO:0140110 | 0.000511614160728 | 0.818181818182 | TADA2B SUPT3H TAF6L SGF29 SUPT7L TERF2 TADA1 TAF5L TADA3 | transcription regulator activity |
| CORUM:1204 | 0.000703183938536 | 0.181818181818 | TERF2IP TERF2 | Rap1 complex |
| CORUM:2766 | 0.000703183938536 | 0.181818181818 | TERF2IP TERF2 | TERF2-RAP1 complex |
| CORUM:1193 | 0.000703183938536 | 0.181818181818 | TERF2IP TERF2 | Rap1 complex |
| CORUM:6641 | 0.000937200833563 | 0.181818181818 | TADA2B TADA3 | USP22-SAGA complex |
| CORUM:6657 | 0.0015050021591 | 0.181818181818 | SGF29 TADA3 | ATAC complex, GCN5-linked |
| GO:0005654 | 0.0021313263302 | 1.0 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TERF2 TADA1 TERF2IP TAF5L TADA3 | nucleoplasm |
| CORUM:6665 | 0.00303854694462 | 0.181818181818 | SGF29 TADA3 | ATAC complex, YEATS2-linked |
| GO:0033276 | 0.00543043333429 | 0.272727272727 | TAF5L TADA3 SUPT3H | transcription factor TFTC complex |
| GO:1905368 | 0.00853763565651 | 0.363636363636 | SUPT20H TADA3 TADA1 SGF29 | peptidase complex |
| GO:0031981 | 0.0170336395485 | 1.0 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TERF2 TADA1 TERF2IP TAF5L TADA3 | nuclear lumen |
| KEGG:03022 | 0.0189255639672 | 0.181818181818 | TAF5L TAF6L | Basal transcription factors |
| GO:0048239 | 0.0247952876258 | 0.181818181818 | TERF2IP TERF2 | negative regulation of DNA recombination at telomere |
| GO:0072695 | 0.0247952876258 | 0.181818181818 | TERF2IP TERF2 | regulation of DNA recombination at telomere |
| GO:0044428 | 0.0345199601716 | 1.0 | TADA2B SUPT3H TAF6L SGF29 SUPT20H SUPT7L TERF2 TADA1 TERF2IP TAF5L TADA3 | nuclear part |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SGF29 | TADA3 | 1.0 | 0.949 | hein_WMM bioplex (SGF29,TADA3) bioplex_WMM Guru youn_WMM hein (SGF29) Malo fraction boldt_WMM |
| TERF2IP | TERF2 | 1.0 | 0.949 | hein_WMM bioplex_WMM hein (TERF2,TERF2IP) Malo fraction |
| SGF29 | SUPT3H | 0.997 | 0.929 | hein_WMM bioplex (SGF29) bioplex_WMM youn_WMM hein (SGF29) |
| SUPT7L | TADA1 | 0.995 | 0.924 | hein_WMM bioplex (TADA1) bioplex_WMM youn_WMM boldt_WMM |
| SGF29 | SUPT20H | 0.994 | 0.919 | hein_WMM bioplex (SGF29) bioplex_WMM youn_WMM hein (SGF29) boldt_WMM |
| SGF29 | TADA2B | 0.987 | 0.901 | hein_WMM bioplex (SGF29,TADA2B) bioplex_WMM youn_WMM hein (SGF29) boldt_WMM |
| SGF29 | SUPT7L | 0.986 | 0.901 | hein_WMM bioplex (SGF29) bioplex_WMM youn_WMM hein (SGF29) boldt_WMM |
| SUPT7L | TADA2B | 0.98 | 0.896 | hein_WMM bioplex (TADA2B) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TADA2B | 0.977 | 0.892 | hein_WMM bioplex (TADA2B) bioplex_WMM youn_WMM boldt_WMM |
| TADA1 | TAF5L | 0.974 | 0.886 | hein_WMM bioplex (TADA1) bioplex_WMM youn_WMM boldt_WMM |
| TERF2 | TADA2B | 0.93 | 0.846 | bioplex (TADA2B) bioplex_WMM |
| TADA1 | TADA2B | 0.888 | 0.818 | hein_WMM bioplex (TADA1,TADA2B) bioplex_WMM youn_WMM boldt_WMM |
| TADA3 | TADA2B | 0.881 | 0.815 | hein_WMM bioplex (TADA2B,TADA3) bioplex_WMM youn_WMM boldt_WMM |
| SGF29 | TAF6L | 0.782 | 0.755 | hein_WMM bioplex (SGF29,TAF6L) bioplex_WMM boldt youn_WMM hein (SGF29) boldt_WMM |
| TERF2IP | TADA2B | 0.767 | 0.75 | bioplex (TADA2B) bioplex_WMM |
| SUPT20H | TADA3 | 0.742 | 0.74 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| TAF6L | TADA2B | 0.734 | 0.738 | hein_WMM bioplex (TADA2B,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT3H | TAF5L | 0.729 | 0.735 | hein_WMM bioplex (TAF5L) bioplex_WMM youn_WMM |
| SGF29 | TAF5L | 0.71 | 0.728 | hein_WMM bioplex (SGF29,TAF5L) bioplex_WMM youn_WMM hein (SGF29) boldt_WMM |
| SUPT3H | TADA2B | 0.669 | 0.702 | hein_WMM bioplex (TADA2B) bioplex_WMM youn_WMM |
| TADA3 | TADA1 | 0.666 | 0.701 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| TAF6L | TADA1 | 0.622 | 0.677 | hein_WMM bioplex (TADA1,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SGF29 | TADA1 | 0.522 | 0.634 | hein_WMM bioplex (SGF29,TADA1) bioplex_WMM youn_WMM hein (SGF29) boldt_WMM |
| TAF6L | SUPT7L | 0.327 | 0.516 | hein_WMM bioplex (TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| TADA3 | SUPT7L | 0.318 | 0.51 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| TADA3 | TAF5L | 0.21 | 0.457 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM boldt_WMM |
| SUPT3H | TAF6L | 0.189 | 0.441 | hein_WMM bioplex (TAF6L) bioplex_WMM youn_WMM |
| TAF6L | TAF5L | 0.151 | 0.411 | hein_WMM bioplex (TAF5L,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TADA1 | 0.115 | 0.384 | hein_WMM bioplex (TADA1) bioplex_WMM youn_WMM boldt_WMM |
| TADA2B | TAF5L | 0.111 | 0.381 | hein_WMM bioplex (TADA2B,TAF5L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT20H | TAF6L | 0.103 | 0.365 | hein_WMM bioplex (TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT3H | TADA3 | 0.064 | 0.348 | hein_WMM bioplex (TADA3) bioplex_WMM youn_WMM |
| SUPT20H | SUPT7L | 0.039 | 0.266 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| SUPT7L | TAF5L | 0.039 | 0.264 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| SUPT20H | TAF5L | 0.037 | 0.263 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| SUPT3H | SUPT7L | 0.031 | 0.24 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| TAF6L | TADA3 | 0.027 | 0.232 | hein_WMM bioplex (TADA3,TAF6L) bioplex_WMM youn_WMM boldt_WMM |
| SUPT3H | TADA1 | 0.026 | 0.218 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| SUPT20H | SUPT3H | 0.023 | 0.206 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| TERF2 | SUPT3H | 0.007 | 0.005 | bioplex_WMM WMM_only |
| TERF2 | TADA1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| TERF2 | SUPT7L | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TERF2 | SUPT20H | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TERF2 | TADA3 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TERF2IP | SUPT3H | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TERF2 | TAF5L | 0.007 | 0.002 | bioplex_WMM WMM_only |
| TERF2IP | TADA1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| TERF2IP | SUPT7L | 0.007 | 0.001 | bioplex_WMM WMM_only |
| TERF2IP | SUPT20H | 0.007 | 0.002 | bioplex_WMM WMM_only |
| TERF2IP | TADA3 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| TERF2IP | TAF5L | 0.007 | 0.005 | bioplex_WMM WMM_only |
| TERF2 | SGF29 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TERF2IP | SGF29 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| TERF2 | TAF6L | 0.006 | 0.003 | bioplex_WMM WMM_only |
| TERF2IP | TAF6L | 0.006 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04123 has an average edge precision of 0.443 which is ranked 2923 out of all 6965 complexes.
Related Complexes