hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04124
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RACK1 | Receptor of activated protein C kinase 1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Small ribosomal subunit protein RACK1) [Cleaved into: Receptor of activated protein C kinase 1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed)] | UniProt NCBI |
| LARP4B | La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5) | UniProt NCBI |
| HELZ | Probable helicase with zinc finger domain (EC 3.6.4.-) (Down-regulated in human cancers protein) | UniProt NCBI |
| MTDH | Protein LYRIC (3D3/LYRIC) (Astrocyte elevated gene-1 protein) (AEG-1) (Lysine-rich CEACAM1 co-isolated protein) (Metadherin) (Metastasis adhesion protein) | UniProt NCBI |
| WIPI1 | WD repeat domain phosphoinositide-interacting protein 1 (WIPI-1) (Atg18 protein homolog) (WD40 repeat protein interacting with phosphoinositides of 49 kDa) (WIPI 49 kDa) | UniProt NCBI |
| PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (PEPCK-C) (EC 4.1.1.32) | UniProt NCBI |
| SNN | Stannin (AG8_1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7011 | 0.0499886427319 | 0.142857142857 | RACK1 | FERMT3-RACK1 complex |
| CORUM:7012 | 0.0499886427319 | 0.142857142857 | RACK1 | ITGB1-RACK1 complex |
| CORUM:7013 | 0.0499886427319 | 0.142857142857 | RACK1 | ITGB2-RACK1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WIPI1 | RACK1 | 0.838 | 0.783 | bioplex (WIPI1) bioplex_WMM |
| LARP4B | RACK1 | 0.185 | 0.439 | hein_WMM youn (LARP4B) bioplex (RACK1) bioplex_WMM gupta_WMM |
| RACK1 | HELZ | 0.113 | 0.382 | bioplex (RACK1) bioplex_WMM gupta_WMM |
| PCK1 | RACK1 | 0.064 | 0.349 | fraction |
| MTDH | LARP4B | 0.044 | 0.277 | hein_WMM youn (LARP4B) bioplex_WMM youn_WMM gupta_WMM fraction |
| SNN | MTDH | 0.024 | 0.214 | bioplex (SNN) bioplex_WMM |
| MTDH | HELZ | 0.007 | 0.008 | youn_WMM gupta_WMM WMM_only |
| MTDH | RACK1 | 0.007 | 0.006 | hein_WMM bioplex (MTDH) gupta_WMM |
| LARP4B | WIPI1 | 0.007 | 0.002 | youn_WMM WMM_only |
| MTDH | WIPI1 | 0.007 | 0.001 | youn_WMM WMM_only |
| SNN | RACK1 | 0.007 | 0.001 | bioplex (SNN) |
| LARP4B | HELZ | 0.005 | 0.012 | youn (LARP4B) bioplex_WMM youn_WMM gupta_WMM |
Images
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Complex HuMAP2_04124 has an average edge precision of 0.206 which is ranked 6087 out of all 6965 complexes.
Related Complexes