hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04126
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GPRC5A | Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Phorbol ester induced gene 1) (PEIG-1) (Retinoic acid-induced gene 1 protein) (RAIG-1) | UniProt NCBI |
| GCNT2 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (EC 2.4.1.150) (I-branching enzyme) (IGNT) | UniProt NCBI |
| FLOT2 | Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1) | UniProt NCBI |
| DSG2 | Desmoglein-2 (Cadherin family member 5) (HDGC) | UniProt NCBI |
| TMEM79 | Transmembrane protein 79 (Mattrin) | UniProt NCBI |
| MPZL3 | Myelin protein zero-like protein 3 | UniProt NCBI |
| FLOT1 | Flotillin-1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8849932 | 0.00599180765553 | 0.285714285714 | FLOT1 FLOT2 | Synaptic adhesion-like molecules |
| GO:0044291 | 0.0362050681854 | 0.428571428571 | DSG2 FLOT2 FLOT1 | cell-cell contact zone |
| GO:0034113 | 0.0417514312642 | 0.428571428571 | DSG2 GCNT2 FLOT1 | heterotypic cell-cell adhesion |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FLOT2 | FLOT1 | 0.99 | 0.909 | hein_WMM bioplex_WMM youn_WMM hein (FLOT1,FLOT2) |
| FLOT2 | TMEM79 | 0.978 | 0.894 | bioplex (FLOT2) bioplex_WMM |
| MPZL3 | FLOT2 | 0.887 | 0.818 | bioplex (FLOT2) bioplex_WMM |
| TMEM79 | GCNT2 | 0.316 | 0.51 | bioplex (TMEM79) bioplex_WMM |
| MPZL3 | TMEM79 | 0.169 | 0.426 | bioplex (TMEM79) bioplex_WMM |
| DSG2 | FLOT2 | 0.078 | 0.353 | hein_WMM bioplex (FLOT2) bioplex_WMM youn_WMM hein (FLOT2) gupta_WMM |
| FLOT2 | GPRC5A | 0.049 | 0.293 | hein_WMM hein (FLOT2) gupta_WMM |
| DSG2 | FLOT1 | 0.023 | 0.209 | hein_WMM bioplex_WMM youn_WMM hein (FLOT1) |
| FLOT1 | GPRC5A | 0.014 | 0.137 | hein_WMM hein (FLOT1) |
| MPZL3 | GCNT2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| MPZL3 | DSG2 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| DSG2 | TMEM79 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| DSG2 | GCNT2 | 0.006 | 0.005 | bioplex (GCNT2) |
| DSG2 | GPRC5A | 0.005 | 0.013 | hein_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_04126 has an average edge precision of 0.332 which is ranked 4205 out of all 6965 complexes.
Related Complexes