hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04131
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PRKRA | Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator) | UniProt NCBI |
| DHX16 | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.4.13) (ATP-dependent RNA helicase #3) (DEAH-box protein 16) | UniProt NCBI |
| ILF3 | Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80) | UniProt NCBI |
| ILF2 | Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa) | UniProt NCBI |
| ZFR2 | Zinc finger RNA-binding protein 2 | UniProt NCBI |
| STRBP | Spermatid perinuclear RNA-binding protein | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003725 | 3.4435733921e-07 | 0.833333333333 | PRKRA ZFR2 STRBP ILF2 ILF3 | double-stranded RNA binding |
| CORUM:5183 | 0.000234668084372 | 0.333333333333 | ILF3 ILF2 | DNA-PK-Ku-eIF2-NF90-NF45 complex |
| CORUM:1332 | 0.00158897110565 | 0.333333333333 | ILF3 ILF2 | Large Drosha complex |
| GO:0003723 | 0.0386338629612 | 1.0 | ILF3 STRBP DHX16 ILF2 ZFR2 PRKRA | RNA binding |
| CORUM:3055 | 0.0424488557459 | 0.333333333333 | ILF3 ILF2 | Nop56p-associated pre-rRNA complex |
| CORUM:3079 | 0.0499726005494 | 0.166666666667 | ILF3 | DGCR8-ILF3 complex |
| CORUM:3080 | 0.0499726005494 | 0.166666666667 | ILF3 | ILF3-XPO5 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ILF3 | ILF2 | 1.0 | 0.949 | hein_WMM youn (ILF3) bioplex (ILF2) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| ILF2 | STRBP | 0.936 | 0.85 | bioplex (ILF2,STRBP) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| ILF3 | STRBP | 0.813 | 0.773 | youn (ILF3) bioplex (STRBP) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| DHX16 | ILF2 | 0.105 | 0.37 | youn_WMM gupta_WMM fraction |
| ILF2 | ZFR2 | 0.05 | 0.297 | Guru fraction |
| ILF2 | PRKRA | 0.044 | 0.275 | bioplex (ILF2) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| DHX16 | ILF3 | 0.018 | 0.178 | youn (ILF3) youn_WMM gupta_WMM fraction |
| STRBP | PRKRA | 0.01 | 0.103 | bioplex (STRBP) bioplex_WMM youn_WMM treiber_WMM |
| DHX16 | STRBP | 0.007 | 0.002 | youn_WMM gupta_WMM WMM_only |
| DHX16 | PRKRA | 0.007 | 0.002 | youn_WMM WMM_only |
| ILF3 | PRKRA | 0.004 | 0.012 | youn (ILF3) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
Images
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Complex HuMAP2_04131 has an average edge precision of 0.346 which is ranked 4039 out of all 6965 complexes.
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