hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04142
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DDB1 | DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe) | UniProt NCBI |
| DDB2 | DNA damage-binding protein 2 (DDB p48 subunit) (DDBb) (Damage-specific DNA-binding protein 2) (UV-damaged DNA-binding protein 2) (UV-DDB 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:790 | 1.67592346237e-06 | 1.0 | DDB2 DDB1 | DDB complex |
| CORUM:1162 | 1.67592346237e-05 | 1.0 | DDB2 DDB1 | Ubiquitin E3 ligase (DDB1, DDB2, CUL4A, CUL4B, RBX1) |
| CORUM:726 | 0.000110610948517 | 1.0 | DDB2 DDB1 | DDB2 complex |
| KEGG:03420 | 0.000138019076752 | 1.0 | DDB2 DDB1 | Nucleotide excision repair |
| REAC:R-HSA-5696394 | 0.00117817419405 | 1.0 | DDB2 DDB1 | DNA Damage Recognition in GG-NER |
| KEGG:04120 | 0.00122335090758 | 1.0 | DDB2 DDB1 | Ubiquitin mediated proteolysis |
| REAC:R-HSA-5696400 | 0.00137425723915 | 1.0 | DDB2 DDB1 | Dual Incision in GG-NER |
| REAC:R-HSA-5696395 | 0.00151335888652 | 1.0 | DDB2 DDB1 | Formation of Incision Complex in GG-NER |
| KEGG:05161 | 0.00174128718926 | 1.0 | DDB2 DDB1 | Hepatitis B |
| WP:WP4666 | 0.00388974910314 | 1.0 | DDB2 DDB1 | Hepatitis B infection |
| GO:0031465 | 0.00450823411379 | 1.0 | DDB2 DDB1 | Cul4B-RING E3 ubiquitin ligase complex |
| REAC:R-HSA-5696399 | 0.00584226918984 | 1.0 | DDB2 DDB1 | Global Genome Nucleotide Excision Repair (GG-NER) |
| REAC:R-HSA-5696398 | 0.0100471611569 | 1.0 | DDB2 DDB1 | Nucleotide Excision Repair |
| GO:0070914 | 0.0247952876258 | 1.0 | DDB2 DDB1 | UV-damage excision repair |
| REAC:R-HSA-8951664 | 0.0411120784555 | 1.0 | DDB2 DDB1 | Neddylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDB1 | DDB2 | 0.929 | 0.845 | hein_WMM bioplex (DDB2) bioplex_WMM hein (DDB1) boldt_WMM |
Images
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Complex HuMAP2_04142 has an average edge precision of 0.845 which is ranked 786 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DDB1 | HuMAP2_02235 HuMAP2_04142 HuMAP2_04937 |
| DDB2 | HuMAP2_04142 HuMAP2_04568 HuMAP2_06808 |