hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04163
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DENND5A | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1) | UniProt NCBI |
| RAB6C | Ras-related protein Rab-6C (Rab6-like protein WTH3) | UniProt NCBI |
| RAB6B | Ras-related protein Rab-6B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0042147 | 0.00774864090629 | 1.0 | RAB6C DENND5A RAB6B | retrograde transport, endosome to Golgi |
| REAC:R-HSA-8876198 | 0.0238137546255 | 0.666666666667 | DENND5A RAB6B | RAB GEFs exchange GTP for GDP on RABs |
| GO:0016482 | 0.043337807111 | 1.0 | RAB6C DENND5A RAB6B | cytosolic transport |
| REAC:R-HSA-9007101 | 0.0444303896492 | 0.666666666667 | DENND5A RAB6B | Rab regulation of trafficking |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB6B | RAB6C | 0.41 | 0.569 | bioplex (RAB6B) bioplex_WMM |
| RAB6B | DENND5A | 0.309 | 0.503 | bioplex (RAB6B) bioplex_WMM |
| DENND5A | RAB6C | 0.009 | 0.095 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04163 has an average edge precision of 0.389 which is ranked 3437 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DENND5A | HuMAP2_01634 HuMAP2_04163 |
| RAB6C | HuMAP2_01634 HuMAP2_04163 |
| RAB6B | HuMAP2_00116 HuMAP2_01634 HuMAP2_03796 HuMAP2_04163 |