hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04175
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BOP1 | Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein) | UniProt NCBI |
| WDR12 | Ribosome biogenesis protein WDR12 (WD repeat-containing protein 12) | UniProt NCBI |
| PES1 | Pescadillo homolog | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6856 | 2.25356268047e-10 | 1.0 | BOP1 PES1 WDR12 | PeBoW complex |
| CORUM:6306 | 9.0142507219e-10 | 1.0 | BOP1 PES1 WDR12 | DDX27-PeBoW complex |
| GO:0070545 | 9.08185760231e-07 | 1.0 | BOP1 PES1 WDR12 | PeBoW complex |
| GO:0000463 | 2.59741127426e-05 | 1.0 | BOP1 PES1 WDR12 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO:0000470 | 0.000103533176666 | 1.0 | BOP1 PES1 WDR12 | maturation of LSU-rRNA |
| GO:0030687 | 0.000160839698137 | 1.0 | BOP1 PES1 WDR12 | preribosome, large subunit precursor |
| GO:0030686 | 0.000331851076788 | 1.0 | BOP1 PES1 WDR12 | 90S preribosome |
| REAC:R-HSA-6791226 | 0.00043699470959 | 1.0 | BOP1 PES1 WDR12 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.000513949964862 | 1.0 | BOP1 PES1 WDR12 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.000599447561444 | 1.0 | BOP1 PES1 WDR12 | rRNA processing |
| GO:0042273 | 0.00360649647245 | 1.0 | BOP1 PES1 WDR12 | ribosomal large subunit biogenesis |
| GO:0030684 | 0.00564855215433 | 1.0 | BOP1 PES1 WDR12 | preribosome |
| REAC:R-HSA-8953854 | 0.0206735000409 | 1.0 | BOP1 PES1 WDR12 | Metabolism of RNA |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PES1 | BOP1 | 0.905 | 0.828 | bioplex (PES1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| PES1 | WDR12 | 0.849 | 0.79 | bioplex (PES1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| WDR12 | BOP1 | 0.019 | 0.186 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_04175 has an average edge precision of 0.601 which is ranked 1940 out of all 6965 complexes.
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