hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04186
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TSPO | Translocator protein (Mitochondrial benzodiazepine receptor) (PKBS) (Peripheral-type benzodiazepine receptor) (PBR) | UniProt NCBI |
| PLIN3 | Perilipin-3 (47 kDa mannose 6-phosphate receptor-binding protein) (47 kDa MPR-binding protein) (Cargo selection protein TIP47) (Mannose-6-phosphate receptor-binding protein 1) (Placental protein 17) (PP17) | UniProt NCBI |
| VIPR2 | Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Helodermin-preferring VIP receptor) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) (PACAP-R3) (VPAC2) | UniProt NCBI |
| VDAC1 | Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM) | UniProt NCBI |
| CERS5 | Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5) | UniProt NCBI |
| C15orf61 | Uncharacterized protein C15orf61 | UniProt NCBI |
| PCDHAC2 | Protocadherin alpha-C2 (PCDH-alpha-C2) | UniProt NCBI |
| VEZT | Vezatin | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04979 | 0.0108401162484 | 0.25 | TSPO VDAC1 | Cholesterol metabolism |
| CORUM:7418 | 0.0497224828424 | 0.125 | VDAC1 | HK1-VDAC1 complex |
| CORUM:7529 | 0.0497224828424 | 0.125 | VDAC1 | APP-Abeta42-VDAC1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VIPR2 | PLIN3 | 0.358 | 0.54 | bioplex (VIPR2) bioplex_WMM |
| VIPR2 | VEZT | 0.031 | 0.241 | bioplex (VIPR2) bioplex_WMM |
| C15orf61 | PCDHAC2 | 0.028 | 0.231 | bioplex (PCDHAC2) bioplex_WMM |
| C15orf61 | VIPR2 | 0.028 | 0.231 | bioplex (VIPR2) bioplex_WMM |
| VDAC1 | PLIN3 | 0.028 | 0.23 | bioplex (PLIN3) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| VIPR2 | CERS5 | 0.023 | 0.207 | bioplex (VIPR2) bioplex_WMM |
| VDAC1 | TSPO | 0.02 | 0.185 | bioplex_WMM Guru boldt fraction boldt_WMM |
| CERS5 | VEZT | 0.009 | 0.095 | bioplex_WMM WMM_only |
| C15orf61 | CERS5 | 0.008 | 0.012 | bioplex_WMM WMM_only |
| C15orf61 | VEZT | 0.007 | 0.01 | bioplex_WMM WMM_only |
| VDAC1 | CERS5 | 0.007 | 0.005 | bioplex_WMM WMM_only boldt_WMM |
| C15orf61 | PLIN3 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| PLIN3 | CERS5 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| TSPO | CERS5 | 0.007 | 0.003 | WMM_only boldt_WMM |
| VDAC1 | VIPR2 | 0.007 | 0.005 | bioplex (VIPR2) bioplex_WMM |
| PLIN3 | VEZT | 0.007 | 0.005 | bioplex_WMM WMM_only |
| VDAC1 | C15orf61 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| VDAC1 | VEZT | 0.007 | 0.001 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_04186 has an average edge precision of 0.112 which is ranked 6899 out of all 6965 complexes.
Related Complexes