hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04199
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NAT10 | RNA cytidine acetyltransferase (EC 2.3.1.-) (18S rRNA cytosine acetyltransferase) (N-acetyltransferase 10) (N-acetyltransferase-like protein) (hALP) | UniProt NCBI |
| GNL3 | Guanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin) | UniProt NCBI |
| CEBPZ | CCAAT/enhancer-binding protein zeta (CCAAT-box-binding transcription factor) (CBF) (CCAAT-binding factor) | UniProt NCBI |
| DDX18 | ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb) | UniProt NCBI |
| NOP56 | Nucleolar protein 56 (Nucleolar protein 5A) | UniProt NCBI |
| MYBBP1A | Myb-binding protein 1A | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03008 | 0.000121655342604 | 0.5 | NOP56 GNL3 NAT10 | Ribosome biogenesis in eukaryotes |
| CORUM:3055 | 0.000381179062735 | 0.5 | MYBBP1A NOP56 GNL3 | Nop56p-associated pre-rRNA complex |
| REAC:R-HSA-8868773 | 0.00661628360681 | 0.5 | NOP56 GNL3 NAT10 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.00770517770968 | 0.5 | NOP56 GNL3 NAT10 | rRNA processing |
| GO:0003723 | 0.0386338629612 | 1.0 | DDX18 CEBPZ GNL3 MYBBP1A NAT10 NOP56 | RNA binding |
| REAC:R-HSA-6790901 | 0.0388379782234 | 0.333333333333 | NOP56 NAT10 | rRNA modification in the nucleus and cytosol |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MYBBP1A | GNL3 | 0.98 | 0.896 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| NOP56 | GNL3 | 0.948 | 0.856 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| CEBPZ | NOP56 | 0.761 | 0.749 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| DDX18 | NOP56 | 0.683 | 0.711 | hein_WMM bioplex_WMM Guru youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| NOP56 | MYBBP1A | 0.652 | 0.69 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM fraction boldt_WMM treiber_WMM |
| NOP56 | NAT10 | 0.562 | 0.65 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM treiber_WMM |
| DDX18 | MYBBP1A | 0.042 | 0.27 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| DDX18 | NAT10 | 0.041 | 0.268 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| CEBPZ | MYBBP1A | 0.019 | 0.184 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| NAT10 | GNL3 | 0.016 | 0.158 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| MYBBP1A | NAT10 | 0.013 | 0.147 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| DDX18 | GNL3 | 0.012 | 0.147 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| CEBPZ | NAT10 | 0.01 | 0.12 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| CEBPZ | GNL3 | 0.01 | 0.106 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| CEBPZ | DDX18 | 0.007 | 0.008 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_04199 has an average edge precision of 0.397 which is ranked 3356 out of all 6965 complexes.
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