hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04222
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EEF1A1 | Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7) | UniProt NCBI |
| EEF1G | Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma) | UniProt NCBI |
| SLC39A7 | Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) | UniProt NCBI |
| VARS | Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) | UniProt NCBI |
| EEF1A2 | Elongation factor 1-alpha 2 (EF-1-alpha-2) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1) | UniProt NCBI |
| KTN1 | Kinectin (CG-1 antigen) (Kinesin receptor) | UniProt NCBI |
| NXPH2 | Neurexophilin-2 | UniProt NCBI |
| EEF1AKMT1 | EEF1A lysine methyltransferase 1 (EC 2.1.1.-) (N(6)-adenine-specific DNA methyltransferase 2) (Protein-lysine N-methyltransferase N6AMT2) | UniProt NCBI |
| PBDC1 | Protein PBDC1 (Polysaccharide biosynthesis domain-containing protein 1) | UniProt NCBI |
| TTLL12 | Tubulin--tyrosine ligase-like protein 12 | UniProt NCBI |
| EEF1D | Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) | UniProt NCBI |
| CARS | Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP107 | 3.66965484532e-06 | 0.333333333333 | EEF1A1 EEF1A2 EEF1G EEF1D | Translation Factors |
| REAC:R-HSA-72766 | 1.04687601621e-05 | 0.5 | EEF1A1 EEF1A2 EEF1D VARS EEF1G CARS | Translation |
| REAC:R-HSA-156842 | 0.000156941814104 | 0.333333333333 | EEF1A1 EEF1A2 EEF1G EEF1D | Eukaryotic Translation Elongation |
| REAC:R-HSA-392499 | 0.000212678742663 | 0.75 | EEF1A1 EEF1AKMT1 EEF1A2 EEF1D KTN1 EEF1G TTLL12 CARS VARS | Metabolism of proteins |
| KEGG:05134 | 0.000270399111681 | 0.25 | EEF1A1 EEF1G EEF1A2 | Legionellosis |
| CORUM:1335 | 0.00498697777099 | 0.166666666667 | EEF1A1 EEF1G | SNW1 complex |
| REAC:R-HSA-8876725 | 0.0171411088968 | 0.166666666667 | EEF1AKMT1 EEF1A1 | Protein methylation |
| KEGG:00970 | 0.0251120616417 | 0.166666666667 | CARS VARS | Aminoacyl-tRNA biosynthesis |
| REAC:R-HSA-379716 | 0.0392835928601 | 0.166666666667 | CARS VARS | Cytosolic tRNA aminoacylation |
| KEGG:05140 | 0.0421208202383 | 0.166666666667 | EEF1A1 EEF1A2 | Leishmaniasis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VARS | EEF1A1 | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1) bioplex_WMM hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| VARS | EEF1G | 1.0 | 0.949 | hein_WMM bioplex (EEF1G) bioplex_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EEF1D | EEF1G | 1.0 | 0.949 | hein_WMM bioplex (EEF1D,EEF1G) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EEF1A1 | EEF1D | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1,EEF1D) bioplex_WMM boldt hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| EEF1A1 | EEF1G | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1,EEF1G) bioplex_WMM Guru boldt hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| VARS | EEF1D | 1.0 | 0.949 | hein_WMM bioplex (EEF1D) bioplex_WMM Malo gupta_WMM fraction boldt_WMM |
| EEF1A2 | PBDC1 | 0.99 | 0.908 | bioplex (EEF1A2,PBDC1) bioplex_WMM fraction |
| EEF1A2 | EEF1G | 0.982 | 0.898 | bioplex (EEF1A2,EEF1G) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| PBDC1 | EEF1A1 | 0.954 | 0.861 | bioplex (EEF1A1,PBDC1) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| CARS | EEF1A1 | 0.741 | 0.74 | hein_WMM bioplex (EEF1A1) bioplex_WMM hein (EEF1A1) fraction boldt_WMM treiber_WMM |
| PBDC1 | TTLL12 | 0.638 | 0.686 | bioplex (PBDC1) bioplex_WMM |
| EEF1A2 | EEF1A1 | 0.397 | 0.557 | bioplex (EEF1A1,EEF1A2) bioplex_WMM treiber_WMM |
| CARS | EEF1D | 0.32 | 0.512 | hein_WMM bioplex (EEF1D) bioplex_WMM boldt_WMM |
| CARS | EEF1G | 0.21 | 0.457 | hein_WMM bioplex (EEF1G) bioplex_WMM fraction boldt_WMM treiber_WMM |
| EEF1G | KTN1 | 0.127 | 0.399 | hein_WMM bioplex (EEF1G) bioplex_WMM youn_WMM hein (KTN1) gupta_WMM treiber_WMM |
| NXPH2 | EEF1A2 | 0.123 | 0.394 | bioplex (NXPH2) bioplex_WMM |
| EEF1D | KTN1 | 0.108 | 0.373 | hein_WMM bioplex (EEF1D) bioplex_WMM youn_WMM hein (KTN1) gupta_WMM |
| EEF1A2 | CARS | 0.103 | 0.366 | bioplex (EEF1A2) bioplex_WMM fraction |
| EEF1A2 | VARS | 0.074 | 0.357 | bioplex (EEF1A2) bioplex_WMM fraction |
| EEF1A2 | EEF1D | 0.044 | 0.275 | bioplex (EEF1A2,EEF1D) bioplex_WMM youn_WMM treiber_WMM |
| EEF1A2 | EEF1AKMT1 | 0.03 | 0.236 | bioplex (EEF1AKMT1) bioplex_WMM |
| EEF1A1 | SLC39A7 | 0.024 | 0.214 | hein_WMM bioplex_WMM boldt hein (EEF1A1) boldt_WMM |
| EEF1A1 | TTLL12 | 0.019 | 0.186 | bioplex (EEF1A1) bioplex_WMM fraction treiber_WMM |
| EEF1A1 | KTN1 | 0.016 | 0.159 | hein_WMM bioplex (EEF1A1) bioplex_WMM boldt hein (EEF1A1) boldt_WMM treiber_WMM |
| EEF1A2 | TTLL12 | 0.016 | 0.16 | bioplex (EEF1A2) bioplex_WMM youn_WMM |
| EEF1AKMT1 | EEF1A1 | 0.011 | 0.141 | bioplex (EEF1AKMT1) bioplex_WMM |
| VARS | KTN1 | 0.009 | 0.102 | hein_WMM bioplex_WMM hein (KTN1) treiber_WMM |
| EEF1AKMT1 | TTLL12 | 0.009 | 0.093 | bioplex (EEF1AKMT1) bioplex_WMM |
| EEF1D | TTLL12 | 0.008 | 0.088 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EEF1G | TTLL12 | 0.008 | 0.09 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| VARS | TTLL12 | 0.008 | 0.084 | bioplex_WMM gupta_WMM WMM_only treiber_WMM |
| CARS | KTN1 | 0.008 | 0.026 | hein_WMM bioplex_WMM WMM_only treiber_WMM |
| CARS | SLC39A7 | 0.007 | 0.007 | hein_WMM WMM_only |
| PBDC1 | EEF1G | 0.007 | 0.002 | bioplex (PBDC1) bioplex_WMM |
| PBDC1 | SLC39A7 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| TTLL12 | SLC39A7 | 0.007 | 0.005 | youn_WMM gupta_WMM WMM_only |
| TTLL12 | KTN1 | 0.007 | 0.0 | youn_WMM WMM_only treiber_WMM |
| PBDC1 | KTN1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| EEF1AKMT1 | EEF1G | 0.007 | 0.005 | bioplex (EEF1AKMT1) |
| EEF1D | SLC39A7 | 0.007 | 0.007 | hein_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| VARS | SLC39A7 | 0.007 | 0.004 | hein_WMM gupta_WMM WMM_only |
| NXPH2 | EEF1A1 | 0.007 | 0.004 | bioplex (NXPH2) bioplex_WMM |
| PBDC1 | EEF1D | 0.007 | 0.003 | bioplex (PBDC1) bioplex_WMM treiber_WMM |
| EEF1G | SLC39A7 | 0.007 | 0.006 | hein_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| EEF1AKMT1 | EEF1D | 0.006 | 0.003 | bioplex (EEF1AKMT1) |
| SLC39A7 | KTN1 | 0.006 | 0.003 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| NXPH2 | EEF1G | 0.006 | 0.005 | bioplex (NXPH2) |
| NXPH2 | PBDC1 | 0.005 | 0.009 | bioplex (NXPH2) bioplex_WMM |
| NXPH2 | SLC39A7 | 0.005 | 0.008 | bioplex (NXPH2) |
| EEF1A2 | KTN1 | 0.004 | 0.017 | bioplex (EEF1A2) bioplex_WMM youn_WMM |
| CARS | TTLL12 | 0.0 | 0.007 | bioplex_WMM fraction treiber_WMM |
| CARS | VARS | 0.0 | 0.001 | hein_WMM bioplex_WMM fraction boldt_WMM treiber_WMM |
| PBDC1 | CARS | 0.0 | 0.001 | bioplex_WMM fraction |
| PBDC1 | VARS | 0.0 | 0.0 | bioplex_WMM fraction |
Images
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Complex HuMAP2_04222 has an average edge precision of 0.281 which is ranked 4876 out of all 6965 complexes.
Related Complexes