hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04231
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VIPAS39 | Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction) | UniProt NCBI |
| VPS33B | Vacuolar protein sorting-associated protein 33B (hVPS33B) | UniProt NCBI |
| MATN4 | Matrilin-4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6390 | 3.35600554376e-06 | 0.666666666667 | VPS33B VIPAS39 | Endosomal targeting complex (VIPAS39-VPS33B) |
| HP:0200084 | 5.30332997138e-05 | 0.666666666667 | VPS33B VIPAS39 | Giant cell hepatitis |
| HP:0009806 | 5.30332997138e-05 | 0.666666666667 | VPS33B VIPAS39 | Nephrogenic diabetes insipidus |
| HP:0001884 | 0.000185591618409 | 0.666666666667 | VPS33B VIPAS39 | Talipes calcaneovalgus |
| HP:0002611 | 0.000485986227107 | 0.666666666667 | VPS33B VIPAS39 | Cholestatic liver disease |
| HP:0001667 | 0.000803978270478 | 0.666666666667 | VPS33B VIPAS39 | Right ventricular hypertrophy |
| HP:0002908 | 0.000803978270478 | 0.666666666667 | VPS33B VIPAS39 | Conjugated hyperbilirubinemia |
| HP:0001707 | 0.0016781848244 | 0.666666666667 | VPS33B VIPAS39 | Abnormal right ventricle morphology |
| HP:0001947 | 0.00309925335629 | 0.666666666667 | VPS33B VIPAS39 | Renal tubular acidosis |
| HP:0000873 | 0.00495195349433 | 0.666666666667 | VPS33B VIPAS39 | Diabetes insipidus |
| HP:0000121 | 0.0130957715491 | 0.666666666667 | VPS33B VIPAS39 | Nephrocalcinosis |
| HP:0002904 | 0.0135801907106 | 0.666666666667 | VPS33B VIPAS39 | Hyperbilirubinemia |
| HP:0012115 | 0.017771321972 | 0.666666666667 | VPS33B VIPAS39 | Hepatitis |
| HP:0000124 | 0.0292514239306 | 0.666666666667 | VPS33B VIPAS39 | Renal tubular dysfunction |
| HP:0001942 | 0.0329433889933 | 0.666666666667 | VPS33B VIPAS39 | Metabolic acidosis |
| HP:0000112 | 0.0329433889933 | 0.666666666667 | VPS33B VIPAS39 | Nephropathy |
| HP:0001385 | 0.0368537935068 | 0.666666666667 | VPS33B VIPAS39 | Hip dysplasia |
| GO:0017185 | 0.0378589948753 | 0.666666666667 | VPS33B VIPAS39 | peptidyl-lysine hydroxylation |
| HP:0001714 | 0.0401392937999 | 0.666666666667 | VPS33B VIPAS39 | Ventricular hypertrophy |
| HP:0002804 | 0.0471291092948 | 0.666666666667 | VPS33B VIPAS39 | Arthrogryposis multiplex congenita |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MATN4 | VIPAS39 | 0.111 | 0.381 | bioplex (MATN4) bioplex_WMM |
| VPS33B | MATN4 | 0.11 | 0.379 | bioplex (MATN4) bioplex_WMM |
| VPS33B | VIPAS39 | 0.015 | 0.139 | bioplex_WMM youn_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_04231 has an average edge precision of 0.3 which is ranked 4601 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| VIPAS39 | HuMAP2_03509 HuMAP2_04231 HuMAP2_05151 HuMAP2_05579 |
| VPS33B | HuMAP2_01416 HuMAP2_03509 HuMAP2_04231 HuMAP2_05151 |
| MATN4 | HuMAP2_01894 HuMAP2_04231 HuMAP2_05151 HuMAP2_05579 |