hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04260
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LYPLA1 | Acyl-protein thioesterase 1 (APT-1) (hAPT1) (EC 3.1.2.-) (Lysophospholipase 1) (Lysophospholipase I) (LPL-I) (LysoPLA I) | UniProt NCBI |
| ALDH1B1 | Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase 5) (Aldehyde dehydrogenase family 1 member B1) | UniProt NCBI |
| ALDH6A1 | Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1) | UniProt NCBI |
| ABAT | 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT) | UniProt NCBI |
| ALDH8A1 | 2-aminomuconic semialdehyde dehydrogenase (EC 1.2.1.32) (Aldehyde dehydrogenase 12) (Aldehyde dehydrogenase family 8 member A1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00410 | 3.50210741481e-06 | 0.6 | ALDH6A1 ABAT ALDH1B1 | beta-Alanine metabolism |
| KEGG:00280 | 1.39628931268e-05 | 0.6 | ALDH6A1 ABAT ALDH1B1 | Valine, leucine and isoleucine degradation |
| KEGG:00640 | 0.00239834964959 | 0.4 | ALDH6A1 ABAT | Propanoate metabolism |
| KEGG:00380 | 0.00284609034939 | 0.4 | ALDH1B1 ALDH8A1 | Tryptophan metabolism |
| GO:0016620 | 0.00407078924856 | 0.6 | ALDH6A1 ALDH8A1 ALDH1B1 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| GO:0016903 | 0.00964423896068 | 0.6 | ALDH6A1 ALDH8A1 ALDH1B1 | oxidoreductase activity, acting on the aldehyde or oxo group of donors |
| KEGG:01100 | 0.0121945453342 | 0.8 | ALDH6A1 ALDH1B1 ABAT ALDH8A1 | Metabolic pathways |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ALDH6A1 | ABAT | 0.982 | 0.898 | fraction |
| ALDH6A1 | ALDH1B1 | 0.572 | 0.655 | bioplex_WMM fraction |
| ALDH6A1 | ALDH8A1 | 0.392 | 0.554 | bioplex (ALDH8A1) bioplex_WMM |
| ALDH6A1 | LYPLA1 | 0.206 | 0.454 | fraction |
| ABAT | LYPLA1 | 0.04 | 0.267 | fraction |
| ALDH1B1 | LYPLA1 | 0.009 | 0.09 | fraction |
| ABAT | ALDH1B1 | 0.006 | 0.004 | bioplex (ABAT) treiber_WMM |
| ALDH8A1 | ALDH1B1 | 0.006 | 0.004 | bioplex (ALDH8A1) |
| ALDH8A1 | LYPLA1 | 0.0 | 0.017 | fraction |
| ALDH8A1 | ABAT | 0.0 | 0.016 | fraction |
Images
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Complex HuMAP2_04260 has an average edge precision of 0.296 which is ranked 4661 out of all 6965 complexes.
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