hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04263
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CBR1 | Carbonyl reductase [NADPH] 1 (EC 1.1.1.184) (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (EC 1.1.1.197) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (Prostaglandin-E(2) 9-reductase) (EC 1.1.1.189) (Short chain dehydrogenase/reductase family 21C member 1) | UniProt NCBI |
| UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein) | UniProt NCBI |
| CBR3 | Carbonyl reductase [NADPH] 3 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase 3) (Short chain dehydrogenase/reductase family 21C member 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00590 | 0.000442505993579 | 0.666666666667 | CBR3 CBR1 | Arachidonic acid metabolism |
| KEGG:00980 | 0.000900335185999 | 0.666666666667 | CBR3 CBR1 | Metabolism of xenobiotics by cytochrome P450 |
| WP:WP2884 | 0.00582733399611 | 0.666666666667 | CBR3 CBR1 | NRF2 pathway |
| GO:0004090 | 0.0135228859698 | 0.666666666667 | CBR3 CBR1 | carbonyl reductase (NADPH) activity |
| WP:WP2882 | 0.0314358751755 | 0.666666666667 | CBR3 CBR1 | Nuclear Receptors Meta-Pathway |
| CORUM:2756 | 0.0499776345577 | 0.333333333333 | UBE2V2 | Ubiquitin ligase (UBE2N, UBE2V2) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CBR3 | CBR1 | 0.997 | 0.935 | hein_WMM bioplex (CBR3) bioplex_WMM hein (CBR3) fraction |
| CBR1 | UBE2V2 | 0.041 | 0.271 | bioplex_WMM fraction |
| CBR3 | UBE2V2 | 0.013 | 0.141 | bioplex_WMM fraction |
Images
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Complex HuMAP2_04263 has an average edge precision of 0.449 which is ranked 2883 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CBR1 | HuMAP2_00317 HuMAP2_03473 HuMAP2_04263 HuMAP2_06771 |
| UBE2V2 | HuMAP2_03473 HuMAP2_04263 HuMAP2_05809 HuMAP2_05915 |
| CBR3 | HuMAP2_00009 HuMAP2_00079 HuMAP2_01205 HuMAP2_03473 HuMAP2_04263 HuMAP2_06771 HuMAP2_06892 |