hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
MTERF3	Transcription termination factor 3, mitochondrial (Mitochondrial transcription termination factor 3) (mTERF3) (mTERF domain-containing protein 1, mitochondrial)	UniProt NCBI
NGRN	Neugrin (Mesenchymal stem cell protein DSC92) (Neurite outgrowth-associated protein) (Spinal cord-derived protein FI58G)	UniProt NCBI
RCC1L	RCC1-like G exchanging factor-like protein (RCC1-like) (Williams-Beuren syndrome chromosomal region 16 protein)	UniProt NCBI
PTCD1	Pentatricopeptide repeat-containing protein 1, mitochondrial	UniProt NCBI
YARS2	Tyrosine--tRNA ligase, mitochondrial (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)	UniProt NCBI
TBC1D8	TBC1 domain family member 8 (AD 3) (Vascular Rab-GAP/TBC-containing protein)	UniProt NCBI
TRUB2	Mitochondrial mRNA pseudouridine synthase TRUB2 (EC 5.4.99.-)	UniProt NCBI
MRPL50	39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50) (Mitochondrial large ribosomal subunit protein mL50)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0032543	6.24544452269e-07	0.75	TRUB2 MTERF3 YARS2 NGRN MRPL50 RCC1L	mitochondrial translation
GO:0140053	1.8524383898e-06	0.75	TRUB2 MTERF3 YARS2 NGRN MRPL50 RCC1L	mitochondrial gene expression
GO:0006412	0.00211678038707	0.75	TRUB2 MTERF3 YARS2 NGRN MRPL50 RCC1L	translation
GO:0070131	0.0023070725905	0.375	TRUB2 RCC1L NGRN	positive regulation of mitochondrial translation
GO:0043043	0.0027513437036	0.75	TRUB2 MTERF3 YARS2 NGRN MRPL50 RCC1L	peptide biosynthetic process
GO:0070129	0.00779479116974	0.375	TRUB2 RCC1L NGRN	regulation of mitochondrial translation
GO:0043604	0.00807450788383	0.75	TRUB2 MTERF3 YARS2 NGRN MRPL50 RCC1L	amide biosynthetic process
GO:0006518	0.00830185416777	0.75	TRUB2 MTERF3 YARS2 NGRN MRPL50 RCC1L	peptide metabolic process
GO:0062125	0.0102394198288	0.375	TRUB2 RCC1L NGRN	regulation of mitochondrial gene expression
GO:0044429	0.0283400474726	0.75	MTERF3 YARS2 NGRN MRPL50 RCC1L PTCD1	mitochondrial part
GO:0043603	0.0387561851755	0.75	TRUB2 MTERF3 YARS2 NGRN MRPL50 RCC1L	cellular amide metabolic process

Protein 1	Protein 2	Score	Precision	Evidence
TRUB2	MRPL50	0.626	0.679	hein_WMM bioplex (MRPL50) bioplex_WMM youn_WMM hein (MRPL50)
MRPL50	MTERF3	0.462	0.6	hein_WMM bioplex (MRPL50) bioplex_WMM youn_WMM hein (MRPL50)
MRPL50	RCC1L	0.306	0.501	hein_WMM bioplex (MRPL50) bioplex_WMM hein (MRPL50)
MRPL50	NGRN	0.231	0.47	hein_WMM bioplex (MRPL50) bioplex_WMM youn_WMM hein (MRPL50)
MTERF3	NGRN	0.056	0.315	hein_WMM bioplex_WMM WMM_only
TRUB2	YARS2	0.055	0.309	hein_WMM bioplex (TRUB2) bioplex_WMM
MTERF3	PTCD1	0.051	0.301	bioplex_WMM WMM_only treiber_WMM
MTERF3	RCC1L	0.031	0.24	hein_WMM bioplex_WMM WMM_only
MRPL50	TBC1D8	0.031	0.239	hein_WMM youn_WMM hein (MRPL50)
NGRN	RCC1L	0.028	0.232	hein_WMM bioplex_WMM WMM_only
PTCD1	NGRN	0.027	0.225	bioplex_WMM WMM_only
MRPL50	YARS2	0.023	0.208	hein_WMM bioplex (MRPL50) bioplex_WMM youn_WMM hein (MRPL50)
PTCD1	RCC1L	0.022	0.208	bioplex_WMM WMM_only
TRUB2	NGRN	0.021	0.186	hein_WMM bioplex_WMM WMM_only
TRUB2	MTERF3	0.018	0.177	hein_WMM bioplex_WMM WMM_only treiber_WMM
TRUB2	RCC1L	0.016	0.161	hein_WMM bioplex_WMM WMM_only
TRUB2	PTCD1	0.016	0.164	bioplex_WMM WMM_only treiber_WMM
MRPL50	PTCD1	0.016	0.154	bioplex (MRPL50) bioplex_WMM
NGRN	YARS2	0.015	0.141	hein_WMM bioplex_WMM youn_WMM WMM_only
YARS2	RCC1L	0.014	0.14	hein_WMM bioplex (YARS2) bioplex_WMM
MTERF3	YARS2	0.014	0.137	hein_WMM bioplex_WMM youn_WMM WMM_only
PTCD1	YARS2	0.008	0.085	bioplex_WMM WMM_only
YARS2	TBC1D8	0.008	0.06	hein_WMM youn_WMM WMM_only
RCC1L	TBC1D8	0.008	0.062	hein_WMM WMM_only
MTERF3	TBC1D8	0.008	0.062	hein_WMM WMM_only
NGRN	TBC1D8	0.008	0.012	hein_WMM WMM_only
TRUB2	TBC1D8	0.008	0.012	hein_WMM WMM_only

Click to enlarge

Complex HuMAP2_04266 has an average edge precision of 0.225 which is ranked 5771 out of all 6965 complexes.

Genename	Complexes
MTERF3	HuMAP2_01037 HuMAP2_02650 HuMAP2_04266 HuMAP2_04542 HuMAP2_04762 HuMAP2_06189 HuMAP2_07015
NGRN	HuMAP2_01037 HuMAP2_02650 HuMAP2_04266 HuMAP2_04542 HuMAP2_06189 HuMAP2_07015
RCC1L	HuMAP2_03394 HuMAP2_04215 HuMAP2_04266 HuMAP2_06189 HuMAP2_07015
PTCD1	HuMAP2_01037 HuMAP2_02650 HuMAP2_04266 HuMAP2_04762 HuMAP2_06189 HuMAP2_07015
YARS2	HuMAP2_01037 HuMAP2_02608 HuMAP2_03838 HuMAP2_04266
TBC1D8	HuMAP2_04266
TRUB2	HuMAP2_00000 HuMAP2_01037 HuMAP2_02608 HuMAP2_03838 HuMAP2_04266 HuMAP2_04762
MRPL50	HuMAP2_01036 HuMAP2_03093 HuMAP2_04266 HuMAP2_04542 HuMAP2_04585 HuMAP2_06482 HuMAP2_06691 HuMAP2_07015