hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04271
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UGGT1 | UDP-glucose:glycoprotein glucosyltransferase 1 (UGT1) (hUGT1) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase) (UDP-glucose ceramide glucosyltransferase-like 1) | UniProt NCBI |
| UGGT2 | UDP-glucose:glycoprotein glucosyltransferase 2 (UGT2) (hUGT2) (EC 2.4.1.-) (UDP--Glc:glycoprotein glucosyltransferase 2) (UDP-glucose ceramide glucosyltransferase-like 1) | UniProt NCBI |
| TACO1 | Translational activator of cytochrome c oxidase 1 (Coiled-coil domain-containing protein 44) (Translational activator of mitochondrially-encoded cytochrome c oxidase I) | UniProt NCBI |
| LAMB1 | Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta) | UniProt NCBI |
| RBM42 | RNA-binding protein 42 (RNA-binding motif protein 42) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-901032 | 0.00282729215335 | 0.4 | UGGT2 UGGT1 | ER Quality Control Compartment (ERQC) |
| REAC:R-HSA-901042 | 0.00437263170532 | 0.4 | UGGT2 UGGT1 | Calnexin/calreticulin cycle |
| GO:0003980 | 0.00450823411379 | 0.4 | UGGT2 UGGT1 | UDP-glucose:glycoprotein glucosyltransferase activity |
| REAC:R-HSA-532668 | 0.00799559968784 | 0.4 | UGGT2 UGGT1 | N-glycan trimming in the ER and Calnexin/Calreticulin cycle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RBM42 | UGGT1 | 0.05 | 0.296 | bioplex (RBM42) fraction |
| LAMB1 | UGGT2 | 0.049 | 0.295 | bioplex_WMM fraction |
| UGGT1 | TACO1 | 0.033 | 0.252 | bioplex_WMM fraction |
| LAMB1 | UGGT1 | 0.009 | 0.108 | bioplex_WMM gupta_WMM fraction |
| LAMB1 | TACO1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| UGGT2 | TACO1 | 0.006 | 0.011 | bioplex (UGGT2) bioplex_WMM |
| UGGT2 | UGGT1 | 0.0 | 0.009 | bioplex (UGGT2) bioplex_WMM gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_04271 has an average edge precision of 0.139 which is ranked 6780 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| UGGT1 | HuMAP2_04271 |
| UGGT2 | HuMAP2_01839 HuMAP2_03085 HuMAP2_04169 HuMAP2_04271 HuMAP2_05231 |
| TACO1 | HuMAP2_04271 |
| LAMB1 | HuMAP2_01618 HuMAP2_01839 HuMAP2_03085 HuMAP2_04169 HuMAP2_04271 HuMAP2_05231 |
| RBM42 | HuMAP2_01011 HuMAP2_04229 HuMAP2_04271 |