hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04293
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CELF2 | CUGBP Elav-like family member 2 (CELF-2) (Bruno-like protein 3) (CUG triplet repeat RNA-binding protein 2) (CUG-BP2) (CUG-BP- and ETR-3-like factor 2) (ELAV-type RNA-binding protein 3) (ETR-3) (Neuroblastoma apoptosis-related RNA-binding protein) (hNAPOR) (RNA-binding protein BRUNOL-3) | UniProt NCBI |
| UBAP2L | Ubiquitin-associated protein 2-like (Protein NICE-4) | UniProt NCBI |
| LARP4 | La-related protein 4 (La ribonucleoprotein domain family member 4) | UniProt NCBI |
| HEXA | Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6274 | 0.0499140284799 | 0.25 | HEXA | HEXA-HEXB complex |
| REAC:R-HSA-3656234 | 0.0499190562503 | 0.25 | HEXA | Defective HEXA causes GM2G1 |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HEXA | UBAP2L | 0.141 | 0.405 | bioplex (HEXA) bioplex_WMM fraction |
| LARP4 | UBAP2L | 0.044 | 0.281 | youn (UBAP2L) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| CELF2 | UBAP2L | 0.04 | 0.269 | youn (UBAP2L) youn_WMM fraction |
| CELF2 | LARP4 | 0.008 | 0.01 | youn_WMM WMM_only |
| HEXA | LARP4 | 0.007 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04293 has an average edge precision of 0.193 which is ranked 6271 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CELF2 | HuMAP2_00052 HuMAP2_02493 HuMAP2_04293 HuMAP2_05685 |
| UBAP2L | HuMAP2_02493 HuMAP2_04293 |
| LARP4 | HuMAP2_02493 HuMAP2_04293 HuMAP2_06735 |
| HEXA | HuMAP2_00675 HuMAP2_02493 HuMAP2_04293 HuMAP2_05194 |