hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04322
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SYPL1 | Synaptophysin-like protein 1 (Pantophysin) | UniProt NCBI |
| VAMP2 | Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) | UniProt NCBI |
| VAMP8 | Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04130 | 0.000221829243661 | 0.666666666667 | VAMP2 VAMP8 | SNARE interactions in vesicular transport |
| REAC:R-HSA-432720 | 0.00397787610966 | 0.666666666667 | VAMP2 VAMP8 | Lysosome Vesicle Biogenesis |
| REAC:R-HSA-432722 | 0.00955880978777 | 0.666666666667 | VAMP2 VAMP8 | Golgi Associated Vesicle Biogenesis |
| REAC:R-HSA-199992 | 0.0170598073203 | 0.666666666667 | VAMP2 VAMP8 | trans-Golgi Network Vesicle Budding |
| REAC:R-HSA-8856825 | 0.0261170593829 | 0.666666666667 | VAMP2 VAMP8 | Cargo recognition for clathrin-mediated endocytosis |
| REAC:R-HSA-5250982 | 0.0498572752401 | 0.333333333333 | VAMP2 | Toxicity of tetanus toxin (TeNT) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SYPL1 | VAMP2 | 0.106 | 0.373 | bioplex (SYPL1) bioplex_WMM |
| SYPL1 | VAMP8 | 0.097 | 0.358 | bioplex (SYPL1) bioplex_WMM |
| VAMP8 | VAMP2 | 0.008 | 0.082 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_04322 has an average edge precision of 0.271 which is ranked 5006 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SYPL1 | HuMAP2_00003 HuMAP2_00644 HuMAP2_01353 HuMAP2_04322 |
| VAMP2 | HuMAP2_00644 HuMAP2_00837 HuMAP2_01353 HuMAP2_04322 |
| VAMP8 | HuMAP2_00576 HuMAP2_00644 HuMAP2_02881 HuMAP2_04322 HuMAP2_04412 |