hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04329
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110) | UniProt NCBI |
| STAM2 | Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3677 | 5.02777038712e-06 | 1.0 | HGS STAM2 | RIN1-STAM2-HRS complex |
| REAC:R-HSA-8875360 | 0.000152509035076 | 1.0 | HGS STAM2 | InlB-mediated entry of Listeria monocytogenes into host cell |
| REAC:R-HSA-8876384 | 0.000286582912066 | 1.0 | HGS STAM2 | Listeria monocytogenes entry into host cells |
| REAC:R-HSA-6807004 | 0.000318425457851 | 1.0 | HGS STAM2 | Negative regulation of MET activity |
| REAC:R-HSA-182971 | 0.000502777038712 | 1.0 | HGS STAM2 | EGFR downregulation |
| REAC:R-HSA-917729 | 0.000779304410004 | 1.0 | HGS STAM2 | Endosomal Sorting Complex Required For Transport (ESCRT) |
| GO:0033565 | 0.00135247023414 | 1.0 | HGS STAM2 | ESCRT-0 complex |
| REAC:R-HSA-177929 | 0.00151335888652 | 1.0 | HGS STAM2 | Signaling by EGFR |
| KEGG:04144 | 0.00387576825996 | 1.0 | HGS STAM2 | Endocytosis |
| REAC:R-HSA-6806834 | 0.00440432685912 | 1.0 | HGS STAM2 | Signaling by MET |
| WP:WP437 | 0.00473923453945 | 1.0 | HGS STAM2 | EGF/EGFR Signaling Pathway |
| REAC:R-HSA-8856825 | 0.00656291627866 | 1.0 | HGS STAM2 | Cargo recognition for clathrin-mediated endocytosis |
| REAC:R-HSA-8856828 | 0.0138364241054 | 1.0 | HGS STAM2 | Clathrin-mediated endocytosis |
| REAC:R-HSA-5689880 | 0.0307297326061 | 1.0 | HGS STAM2 | Ub-specific processing proteases |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HGS | STAM2 | 0.988 | 0.901 | Guru youn_WMM Malo gupta_WMM fraction |
Images
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Complex HuMAP2_04329 has an average edge precision of 0.901 which is ranked 546 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HGS | HuMAP2_00820 HuMAP2_00893 HuMAP2_02464 HuMAP2_04329 HuMAP2_04638 HuMAP2_05413 HuMAP2_06440 |
| STAM2 | HuMAP2_00820 HuMAP2_04329 HuMAP2_04638 HuMAP2_05413 HuMAP2_06440 |