hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04334
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CELSR3 | Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) | UniProt NCBI |
| ADGRV1 | Adhesion G-protein coupled receptor V1 (ADGRV1) (EC 3.4.-.-) (G-protein coupled receptor 98) (Monogenic audiogenic seizure susceptibility protein 1 homolog) (Usher syndrome type-2C protein) (Very large G-protein coupled receptor 1) [Cleaved into: ADGRV1 subunit alpha; ADGRV1 subunit beta] | UniProt NCBI |
| GFM2 | Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2) (Elongation factor G2) (hEFG2) | UniProt NCBI |
| RNF157 | E3 ubiquitin ligase RNF157 (EC 2.3.2.27) (RING finger protein 157) (RING-type E3 ubiquitin transferase RNF157) | UniProt NCBI |
| PSG8 | Pregnancy-specific beta-1-glycoprotein 8 (PS-beta-G-8) (PSBG-8) (Pregnancy-specific glycoprotein 8) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP117 | 0.00299893680898 | 0.4 | ADGRV1 CELSR3 | GPCRs, Other |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PSG8 | CELSR3 | 0.126 | 0.399 | bioplex (PSG8) bioplex_WMM |
| PSG8 | RNF157 | 0.073 | 0.355 | bioplex (PSG8) bioplex_WMM |
| PSG8 | GFM2 | 0.027 | 0.224 | bioplex (PSG8) bioplex_WMM |
| PSG8 | ADGRV1 | 0.023 | 0.21 | bioplex (PSG8) bioplex_WMM |
| RNF157 | GFM2 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| CELSR3 | RNF157 | 0.008 | 0.044 | bioplex_WMM WMM_only |
| RNF157 | ADGRV1 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| CELSR3 | GFM2 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| CELSR3 | ADGRV1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| GFM2 | ADGRV1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04334 has an average edge precision of 0.132 which is ranked 6822 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CELSR3 | HuMAP2_00026 HuMAP2_03853 HuMAP2_04334 |
| ADGRV1 | HuMAP2_04334 |
| GFM2 | HuMAP2_04255 HuMAP2_04334 HuMAP2_06671 |
| RNF157 | HuMAP2_00026 HuMAP2_03853 HuMAP2_04334 |
| PSG8 | HuMAP2_00026 HuMAP2_03009 HuMAP2_03853 HuMAP2_04334 HuMAP2_06107 |