hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04335
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RACGAP1 | Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) | UniProt NCBI |
| KIF23 | Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) | UniProt NCBI |
| SHCBP1 | SHC SH2 domain-binding protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:929 | 1.75101820273e-06 | 1.0 | RACGAP1 SHCBP1 KIF23 | CEN complex |
| CORUM:7440 | 3.35600554376e-06 | 0.666666666667 | RACGAP1 KIF23 | KIF23-RACGAP1 complex |
| CORUM:7439 | 1.00675659188e-05 | 0.666666666667 | RACGAP1 KIF23 | ECT2-KIF23-RACGAP1 complex |
| GO:0097149 | 0.00405722906526 | 0.666666666667 | RACGAP1 KIF23 | centralspindlin complex |
| REAC:R-HSA-983189 | 0.0106595435179 | 0.666666666667 | RACGAP1 KIF23 | Kinesins |
| GO:0051256 | 0.0283955176165 | 0.666666666667 | RACGAP1 KIF23 | mitotic spindle midzone assembly |
| MIRNA:hsa-miR-1183 | 0.0286699333993 | 0.666666666667 | RACGAP1 SHCBP1 | hsa-miR-1183 |
| REAC:R-HSA-6811434 | 0.0304025344128 | 0.666666666667 | RACGAP1 KIF23 | COPI-dependent Golgi-to-ER retrograde traffic |
| GO:0051255 | 0.0378589948753 | 0.666666666667 | RACGAP1 KIF23 | spindle midzone assembly |
| REAC:R-HSA-2132295 | 0.0444303896492 | 0.666666666667 | RACGAP1 KIF23 | MHC class II antigen presentation |
| GO:0000022 | 0.0486736709081 | 0.666666666667 | RACGAP1 KIF23 | mitotic spindle elongation |
| GO:0051231 | 0.0486736709081 | 0.666666666667 | RACGAP1 KIF23 | spindle elongation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RACGAP1 | KIF23 | 1.0 | 0.949 | hein_WMM bioplex (RACGAP1) bioplex_WMM Guru youn_WMM hein (KIF23,RACGAP1) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SHCBP1 | RACGAP1 | 0.957 | 0.863 | hein_WMM bioplex (RACGAP1) bioplex_WMM youn_WMM hein (RACGAP1,SHCBP1) boldt_WMM |
| SHCBP1 | KIF23 | 0.061 | 0.334 | hein_WMM bioplex_WMM youn_WMM hein (KIF23,SHCBP1) gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_04335 has an average edge precision of 0.715 which is ranked 1324 out of all 6965 complexes.
Related Complexes