hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04352
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP2A2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase) | UniProt NCBI |
| ATP1A1 | Sodium/potassium-transporting ATPase subunit alpha-1 (Na(+)/K(+) ATPase alpha-1 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04260 | 0.000415808000786 | 1.0 | ATP1A1 ATP2A2 | Cardiac muscle contraction |
| KEGG:04972 | 0.000472708042999 | 1.0 | ATP1A1 ATP2A2 | Pancreatic secretion |
| KEGG:04919 | 0.00092323965929 | 1.0 | ATP1A1 ATP2A2 | Thyroid hormone signaling pathway |
| KEGG:04261 | 0.00120453012438 | 1.0 | ATP1A1 ATP2A2 | Adrenergic signaling in cardiomyocytes |
| KEGG:04022 | 0.00144000876062 | 1.0 | ATP1A1 ATP2A2 | cGMP-PKG signaling pathway |
| REAC:R-HSA-5578775 | 0.00165916422775 | 1.0 | ATP1A1 ATP2A2 | Ion homeostasis |
| REAC:R-HSA-936837 | 0.00181167326283 | 1.0 | ATP1A1 ATP2A2 | Ion transport by P-type ATPases |
| KEGG:04024 | 0.00209581822151 | 1.0 | ATP1A1 ATP2A2 | cAMP signaling pathway |
| REAC:R-HSA-5576891 | 0.00986448549954 | 1.0 | ATP1A1 ATP2A2 | Cardiac conduction |
| REAC:R-HSA-983712 | 0.0213177464414 | 1.0 | ATP1A1 ATP2A2 | Ion channel transport |
| REAC:R-HSA-397014 | 0.0246461304377 | 1.0 | ATP1A1 ATP2A2 | Muscle contraction |
| CORUM:6507 | 0.0249595281251 | 0.5 | ATP2A2 | SERCA-PLN complex |
| CORUM:6516 | 0.0249595281251 | 0.5 | ATP2A2 | SLN-PLN-SERCA2A complex |
| KEGG:04964 | 0.0434293219628 | 0.5 | ATP1A1 | Proximal tubule bicarbonate reclamation |
| HP:0008410 | 0.0497341708567 | 0.5 | ATP2A2 | Subungual hyperkeratotic fragments |
| HP:0012169 | 0.0497341708567 | 0.5 | ATP1A1 | Self-biting |
| CORUM:6510 | 0.0499173803268 | 0.5 | ATP2A2 | ILK-SERCA2A-PLN complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP1A1 | ATP2A2 | 0.736 | 0.738 | hein_WMM bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_04352 has an average edge precision of 0.738 which is ranked 1213 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATP2A2 | HuMAP2_02393 HuMAP2_02541 HuMAP2_04352 HuMAP2_05501 |
| ATP1A1 | HuMAP2_00221 HuMAP2_02063 HuMAP2_02393 HuMAP2_04352 HuMAP2_05949 |