hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04379
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KLK8 | Kallikrein-8 (hK8) (EC 3.4.21.118) (Neuropsin) (NP) (Ovasin) (Serine protease 19) (Serine protease TADG-14) (Tumor-associated differentially expressed gene 14 protein) | UniProt NCBI |
| TAMM41 | Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41) | UniProt NCBI |
| ERO1B | ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic reticulum oxidoreductase beta) (Endoplasmic reticulum oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta) | UniProt NCBI |
| LIPC | Hepatic triacylglycerol lipase (HL) (Hepatic lipase) (EC 3.1.1.3) (Lipase member C) | UniProt NCBI |
| ATP4A | Potassium-transporting ATPase alpha chain 1 (EC 7.2.2.19) (Gastric H(+)/K(+) ATPase subunit alpha) (Proton pump) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6436 | 0.0249780992026 | 0.2 | ATP4A | ATP4A-ATP4B complex |
| WP:WP2597 | 0.0372906105173 | 0.2 | ATP4A | Secretion of Hydrochloric Acid in Parietal Cells |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP4A | KLK8 | 0.441 | 0.584 | bioplex (KLK8) bioplex_WMM |
| ATP4A | ERO1B | 0.085 | 0.349 | bioplex (ERO1B) bioplex_WMM |
| KLK8 | TAMM41 | 0.035 | 0.265 | bioplex (KLK8) bioplex_WMM |
| ATP4A | LIPC | 0.03 | 0.234 | bioplex (LIPC) bioplex_WMM |
| ATP4A | TAMM41 | 0.007 | 0.006 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04379 has an average edge precision of 0.288 which is ranked 4779 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KLK8 | HuMAP2_02983 HuMAP2_03190 HuMAP2_04379 |
| TAMM41 | HuMAP2_03372 HuMAP2_04379 |
| ERO1B | HuMAP2_00147 HuMAP2_00280 HuMAP2_04379 HuMAP2_05789 |
| LIPC | HuMAP2_04379 HuMAP2_05645 |
| ATP4A | HuMAP2_00147 HuMAP2_03190 HuMAP2_04379 HuMAP2_05645 |