hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04382
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DEPDC5 | GATOR complex protein DEPDC5 (DEP domain-containing protein 5) | UniProt NCBI |
| NPRL2 | GATOR complex protein NPRL2 (Gene 21 protein) (G21 protein) (Nitrogen permease regulator 2-like protein) (NPR2-like protein) (Tumor suppressor candidate 4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6215 | 5.02777038712e-06 | 1.0 | DEPDC5 NPRL2 | GATOR1 complex |
| CORUM:6217 | 4.69258569465e-05 | 1.0 | DEPDC5 NPRL2 | GATOR complex |
| HP:0032046 | 0.000120219576368 | 1.0 | DEPDC5 NPRL2 | Focal cortical dysplasia |
| KEGG:04150 | 0.00150216111442 | 1.0 | DEPDC5 NPRL2 | mTOR signaling pathway |
| GO:1990130 | 0.00676235117068 | 1.0 | DEPDC5 NPRL2 | GATOR1 complex |
| HP:0002539 | 0.00806472991466 | 1.0 | DEPDC5 NPRL2 | Cortical dysplasia |
| HP:0003829 | 0.0254665135939 | 1.0 | DEPDC5 NPRL2 | Incomplete penetrance |
| HP:0032047 | 0.0497341708567 | 0.5 | DEPDC5 | Focal cortical dysplasia type I |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DEPDC5 | NPRL2 | 0.773 | 0.752 | bioplex (DEPDC5,NPRL2) bioplex_WMM |
Images
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Complex HuMAP2_04382 has an average edge precision of 0.752 which is ranked 1133 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DEPDC5 | HuMAP2_00503 HuMAP2_00701 HuMAP2_01040 HuMAP2_01293 HuMAP2_04382 |
| NPRL2 | HuMAP2_00503 HuMAP2_01040 HuMAP2_01293 HuMAP2_04382 |