hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04386
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRAPPC4 | Trafficking protein particle complex subunit 4 (Hematopoietic stem/progenitor cell protein 172) (Synbindin) (TRS23 homolog) | UniProt NCBI |
| TRAPPC1 | Trafficking protein particle complex subunit 1 (BET5 homolog) (Multiple myeloma protein 2) (MUM-2) | UniProt NCBI |
| TRAPPC3 | Trafficking protein particle complex subunit 3 (BET3 homolog) | UniProt NCBI |
| MAP11 | Microtubule-associated protein 11 | UniProt NCBI |
| TRAPPC13 | Trafficking protein particle complex subunit 13 | UniProt NCBI |
| TRAPPC6B | Trafficking protein particle complex subunit 6B (TRAPP complex subunit 6B) | UniProt NCBI |
| TRAPPC5 | Trafficking protein particle complex subunit 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6468 | 1.44831279607e-13 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | TRAPP complex |
| REAC:R-HSA-8876198 | 3.36474050891e-11 | 0.857142857143 | TRAPPC1 TRAPPC4 TRAPPC13 TRAPPC3 TRAPPC6B TRAPPC5 | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 2.27870020144e-10 | 0.857142857143 | TRAPPC1 TRAPPC4 TRAPPC13 TRAPPC3 TRAPPC6B TRAPPC5 | Rab regulation of trafficking |
| REAC:R-HSA-204005 | 3.40143577456e-09 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | COPII-mediated vesicle transport |
| GO:0030008 | 1.79134017731e-07 | 0.571428571429 | TRAPPC1 TRAPPC3 TRAPPC5 TRAPPC4 | TRAPP complex |
| REAC:R-HSA-199977 | 2.72460599101e-07 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | ER to Golgi Anterograde Transport |
| REAC:R-HSA-948021 | 6.11291954817e-07 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | Transport to the Golgi and subsequent modification |
| GO:0048207 | 9.33771078807e-07 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | vesicle targeting, rough ER to cis-Golgi |
| GO:0048208 | 9.33771078807e-07 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | COPII vesicle coating |
| GO:0006901 | 1.3030002824e-06 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | vesicle coating |
| GO:0090114 | 1.52694419847e-06 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | COPII-coated vesicle budding |
| GO:0048199 | 1.78064392213e-06 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | vesicle targeting, to, from or within Golgi |
| GO:0048194 | 2.56432453108e-06 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | Golgi vesicle budding |
| REAC:R-HSA-199991 | 3.8900451489e-06 | 0.857142857143 | TRAPPC1 TRAPPC4 TRAPPC13 TRAPPC3 TRAPPC6B TRAPPC5 | Membrane Trafficking |
| GO:0006903 | 5.26406769004e-06 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | vesicle targeting |
| REAC:R-HSA-5653656 | 5.36316718014e-06 | 0.857142857143 | TRAPPC1 TRAPPC4 TRAPPC13 TRAPPC3 TRAPPC6B TRAPPC5 | Vesicle-mediated transport |
| GO:0006900 | 8.37777986794e-06 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | vesicle budding from membrane |
| REAC:R-HSA-446203 | 8.43219987917e-06 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | Asparagine N-linked glycosylation |
| GO:0017112 | 4.44842942078e-05 | 0.571428571429 | TRAPPC1 TRAPPC3 TRAPPC5 TRAPPC4 | Rab guanyl-nucleotide exchange factor activity |
| GO:0051650 | 0.000130163302766 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | establishment of vesicle localization |
| GO:0051648 | 0.000166994060938 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | vesicle localization |
| GO:0006888 | 0.00027293231344 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO:0099023 | 0.000310987597034 | 0.571428571429 | TRAPPC1 TRAPPC3 TRAPPC5 TRAPPC4 | vesicle tethering complex |
| GO:0005088 | 0.00154914988886 | 0.571428571429 | TRAPPC1 TRAPPC3 TRAPPC5 TRAPPC4 | Ras guanyl-nucleotide exchange factor activity |
| GO:0016050 | 0.0018532045628 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | vesicle organization |
| GO:0051656 | 0.00402812703237 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | establishment of organelle localization |
| GO:0048193 | 0.00532589578057 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | Golgi vesicle transport |
| GO:0017137 | 0.0120844889275 | 0.571428571429 | TRAPPC1 TRAPPC3 TRAPPC5 TRAPPC4 | Rab GTPase binding |
| REAC:R-HSA-597592 | 0.0130103492531 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | Post-translational protein modification |
| GO:0005085 | 0.0187784910979 | 0.571428571429 | TRAPPC1 TRAPPC3 TRAPPC5 TRAPPC4 | guanyl-nucleotide exchange factor activity |
| GO:0051640 | 0.0371718917346 | 0.714285714286 | TRAPPC1 TRAPPC3 TRAPPC4 TRAPPC6B TRAPPC5 | organelle localization |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TRAPPC1 | TRAPPC4 | 0.967 | 0.877 | bioplex (TRAPPC1) bioplex_WMM boldt boldt_WMM |
| TRAPPC5 | TRAPPC3 | 0.902 | 0.826 | hein_WMM bioplex (TRAPPC5) bioplex_WMM youn_WMM fraction boldt_WMM |
| TRAPPC1 | TRAPPC3 | 0.882 | 0.818 | hein_WMM bioplex (TRAPPC1) bioplex_WMM boldt boldt_WMM |
| TRAPPC1 | TRAPPC5 | 0.653 | 0.69 | hein_WMM bioplex (TRAPPC1,TRAPPC5) bioplex_WMM boldt_WMM |
| TRAPPC6B | TRAPPC1 | 0.619 | 0.676 | bioplex (TRAPPC1) bioplex_WMM boldt_WMM |
| TRAPPC5 | TRAPPC4 | 0.601 | 0.671 | bioplex (TRAPPC5) bioplex_WMM boldt_WMM |
| TRAPPC6B | TRAPPC5 | 0.577 | 0.659 | bioplex (TRAPPC5) bioplex_WMM boldt_WMM |
| TRAPPC5 | TRAPPC13 | 0.545 | 0.642 | hein_WMM bioplex (TRAPPC5) bioplex_WMM |
| TRAPPC5 | MAP11 | 0.538 | 0.642 | bioplex (TRAPPC5) bioplex_WMM boldt_WMM |
| TRAPPC1 | TRAPPC13 | 0.32 | 0.511 | hein_WMM bioplex (TRAPPC1) bioplex_WMM |
| TRAPPC1 | MAP11 | 0.21 | 0.457 | bioplex (TRAPPC1) bioplex_WMM boldt_WMM |
| MAP11 | TRAPPC4 | 0.026 | 0.218 | bioplex_WMM WMM_only boldt_WMM |
| MAP11 | TRAPPC3 | 0.017 | 0.176 | bioplex_WMM WMM_only boldt_WMM |
| TRAPPC6B | MAP11 | 0.015 | 0.139 | bioplex_WMM WMM_only boldt_WMM |
| TRAPPC6B | TRAPPC13 | 0.013 | 0.152 | bioplex_WMM WMM_only |
| TRAPPC3 | TRAPPC13 | 0.013 | 0.151 | hein_WMM bioplex_WMM WMM_only |
| TRAPPC4 | TRAPPC3 | 0.012 | 0.144 | bioplex_WMM Guru boldt fraction boldt_WMM |
| MAP11 | TRAPPC13 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| TRAPPC4 | TRAPPC13 | 0.005 | 0.011 | bioplex_WMM fraction |
| TRAPPC6B | TRAPPC3 | 0.0 | 0.019 | bioplex_WMM Guru fraction boldt_WMM |
| TRAPPC6B | TRAPPC4 | 0.0 | 0.003 | bioplex_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_04386 has an average edge precision of 0.408 which is ranked 3216 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TRAPPC4 | HuMAP2_00881 HuMAP2_01778 HuMAP2_04386 |
| TRAPPC1 | HuMAP2_00881 HuMAP2_01778 HuMAP2_04386 |
| TRAPPC3 | HuMAP2_00881 HuMAP2_04386 |
| MAP11 | HuMAP2_00881 HuMAP2_04386 HuMAP2_05875 |
| TRAPPC13 | HuMAP2_00881 HuMAP2_04386 |
| TRAPPC6B | HuMAP2_00881 HuMAP2_04386 |
| TRAPPC5 | HuMAP2_00881 HuMAP2_04386 |