hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04402
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HSD17B8 | Estradiol 17-beta-dehydrogenase 8 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit) (KAR alpha subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Protein Ke6) (Ke-6) (Really interesting new gene 2 protein) (Short chain dehydrogenase/reductase family 30C member 1) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.239) | UniProt NCBI |
| CBR4 | Carbonyl reductase family member 4 (EC 1.-.-.-) (3-ketoacyl-[acyl-carrier-protein] reductase beta subunit) (KAR beta subunit) (3-oxoacyl-[acyl-carrier-protein] reductase) (EC 1.1.1.-) (Quinone reductase CBR4) (Short chain dehydrogenase/reductase family 45C member 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00061 | 1.75077052963e-05 | 1.0 | HSD17B8 CBR4 | Fatty acid biosynthesis |
| KEGG:01212 | 0.000201046815819 | 1.0 | HSD17B8 CBR4 | Fatty acid metabolism |
| GO:0047025 | 0.000450823411379 | 1.0 | HSD17B8 CBR4 | 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity |
| REAC:R-HSA-75105 | 0.000779304410004 | 1.0 | HSD17B8 CBR4 | Fatty acyl-CoA biosynthesis |
| GO:0048038 | 0.0162296428096 | 1.0 | HSD17B8 CBR4 | quinone binding |
| REAC:R-HSA-8978868 | 0.0194876380205 | 1.0 | HSD17B8 CBR4 | Fatty acid metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CBR4 | HSD17B8 | 0.899 | 0.823 | bioplex (HSD17B8) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_04402 has an average edge precision of 0.823 which is ranked 862 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HSD17B8 | HuMAP2_02684 HuMAP2_03791 HuMAP2_03901 HuMAP2_04402 |
| CBR4 | HuMAP2_02684 HuMAP2_03791 HuMAP2_03901 HuMAP2_04402 |