hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04406
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| C2CD2 | C2 domain-containing protein 2 (Transmembrane protein 24-like) | UniProt NCBI |
| ARHGAP26 | Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) | UniProt NCBI |
| ARHGAP10 | Rho GTPase-activating protein 10 (GTPase regulator associated with focal adhesion kinase 2) (Graf-related protein 2) (Rho-type GTPase-activating protein 10) | UniProt NCBI |
| OPHN1 | Oligophrenin-1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-194840 | 0.000491277204617 | 0.75 | ARHGAP26 OPHN1 ARHGAP10 | Rho GTPase cycle |
| REAC:R-HSA-194315 | 0.0173883634433 | 0.75 | ARHGAP26 OPHN1 ARHGAP10 | Signaling by Rho GTPases |
| CORUM:5274 | 0.0499140284799 | 0.25 | ARHGAP10 | Cell-cell junction complex (ARHGAP10-CTNNA1) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ARHGAP26 | ARHGAP10 | 0.981 | 0.896 | bioplex (ARHGAP26) bioplex_WMM boldt boldt_WMM |
| OPHN1 | ARHGAP26 | 0.786 | 0.758 | bioplex (ARHGAP26) bioplex_WMM |
| C2CD2 | ARHGAP26 | 0.651 | 0.69 | bioplex (C2CD2) bioplex_WMM |
| C2CD2 | ARHGAP10 | 0.632 | 0.681 | bioplex (C2CD2) bioplex_WMM |
| OPHN1 | ARHGAP10 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04406 has an average edge precision of 0.623 which is ranked 1811 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| C2CD2 | HuMAP2_00400 HuMAP2_02734 HuMAP2_03108 HuMAP2_04406 |
| ARHGAP26 | HuMAP2_01128 HuMAP2_02734 HuMAP2_03108 HuMAP2_04406 |
| ARHGAP10 | HuMAP2_01128 HuMAP2_02734 HuMAP2_03108 HuMAP2_04406 |
| OPHN1 | HuMAP2_01128 HuMAP2_02734 HuMAP2_03108 HuMAP2_04406 |