hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_04413

Confidence: Medium High

Genename	Protein Name	Links
SPOCK1	Testican-1 (Protein SPOCK)	UniProt NCBI
NHSL1	NHS-like protein 1	UniProt NCBI
GTF2E2	Transcription initiation factor IIE subunit beta (TFIIE-beta) (General transcription factor IIE subunit 2)	UniProt NCBI
GTF2E1	General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:152	5.02777038712e-06	0.5	GTF2E2 GTF2E1	TFIIE complex
WP:WP405	0.00137286558226	0.5	GTF2E2 GTF2E1	Eukaryotic Transcription Initiation
CORUM:103	0.00138493273707	0.5	GTF2E2 GTF2E1	RNA polymerase II holoenzyme complex
CORUM:2825	0.00163051620808	0.5	GTF2E2 GTF2E1	BRCA1-RNA polymerase II complex
KEGG:03022	0.00171897863478	0.5	GTF2E2 GTF2E1	Basal transcription factors
GO:0005673	0.00270494046827	0.5	GTF2E2 GTF2E1	transcription factor TFIIE complex
REAC:R-HSA-73779	0.0108262926188	0.5	GTF2E2 GTF2E1	RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REAC:R-HSA-76042	0.0108262926188	0.5	GTF2E2 GTF2E1	RNA Polymerase II Transcription Initiation And Promoter Clearance
REAC:R-HSA-75953	0.0108262926188	0.5	GTF2E2 GTF2E1	RNA Polymerase II Transcription Initiation
REAC:R-HSA-167162	0.0108262926188	0.5	GTF2E2 GTF2E1	RNA Polymerase II HIV Promoter Escape
REAC:R-HSA-167161	0.0108262926188	0.5	GTF2E2 GTF2E1	HIV Transcription Initiation
REAC:R-HSA-73776	0.0108262926188	0.5	GTF2E2 GTF2E1	RNA Polymerase II Promoter Escape
GO:0001097	0.0162267366884	0.5	GTF2E2 GTF2E1	TFIIH-class transcription factor complex binding
REAC:R-HSA-167172	0.0248339118539	0.5	GTF2E2 GTF2E1	Transcription of the HIV genome
REAC:R-HSA-6807505	0.0269852439715	0.5	GTF2E2 GTF2E1	RNA polymerase II transcribes snRNA genes
REAC:R-HSA-674695	0.0331557329305	0.5	GTF2E2 GTF2E1	RNA Polymerase II Pre-transcription Events
KEGG:05203	0.03463652866	0.5	GTF2E2 GTF2E1	Viral carcinogenesis

Protein 1	Protein 2	Score	Precision	Evidence
GTF2E2	GTF2E1	1.0	0.949	hein_WMM bioplex (GTF2E2) bioplex_WMM Guru youn_WMM hein (GTF2E2) gupta_WMM fraction
GTF2E2	SPOCK1	0.165	0.42	hein_WMM hein (GTF2E2)
GTF2E2	NHSL1	0.078	0.352	hein_WMM hein (GTF2E2)
GTF2E1	SPOCK1	0.008	0.083	hein_WMM WMM_only
GTF2E1	NHSL1	0.008	0.023	hein_WMM WMM_only
SPOCK1	NHSL1	0.008	0.023	hein_WMM WMM_only

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ComplexPrecisionDistribution

Complex HuMAP2_04413 has an average edge precision of 0.308 which is ranked 4473 out of all 6965 complexes.

Related Complexes

Genename	Complexes
SPOCK1	HuMAP2_00694 HuMAP2_04413 HuMAP2_04857 HuMAP2_05709
NHSL1	HuMAP2_04106 HuMAP2_04413 HuMAP2_04857 HuMAP2_05709
GTF2E2	HuMAP2_00481 HuMAP2_00694 HuMAP2_02992 HuMAP2_04413 HuMAP2_04857 HuMAP2_05709 HuMAP2_06800
GTF2E1	HuMAP2_00481 HuMAP2_00694 HuMAP2_02992 HuMAP2_04413 HuMAP2_04857 HuMAP2_06800