hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04416
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| YBX1 | Nuclease-sensitive element-binding protein 1 (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Y-box transcription factor) (Y-box-binding protein 1) (YB-1) | UniProt NCBI |
| RPL28 | 60S ribosomal protein L28 (Large ribosomal subunit protein eL28) | UniProt NCBI |
| RPLP0 | 60S acidic ribosomal protein P0 (60S ribosomal protein L10E) (Large ribosomal subunit protein uL10) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3055 | 3.86936712237e-05 | 1.0 | YBX1 RPL28 RPLP0 | Nop56p-associated pre-rRNA complex |
| CORUM:308 | 0.0034666239215 | 0.666666666667 | RPL28 RPLP0 | 60S ribosomal subunit, cytoplasmic |
| WP:WP477 | 0.00357470816736 | 0.666666666667 | RPL28 RPLP0 | Cytoplasmic Ribosomal Proteins |
| KEGG:03010 | 0.00373360278335 | 0.666666666667 | RPL28 RPLP0 | Ribosome |
| CORUM:306 | 0.0103042111837 | 0.666666666667 | RPL28 RPLP0 | Ribosome, cytoplasmic |
| REAC:R-HSA-8953854 | 0.0206735000409 | 1.0 | YBX1 RPL28 RPLP0 | Metabolism of RNA |
| REAC:R-HSA-192823 | 0.0255313065434 | 0.666666666667 | RPL28 RPLP0 | Viral mRNA Translation |
| REAC:R-HSA-156902 | 0.0255313065434 | 0.666666666667 | RPL28 RPLP0 | Peptide chain elongation |
| REAC:R-HSA-72764 | 0.0279140119136 | 0.666666666667 | RPL28 RPLP0 | Eukaryotic Translation Termination |
| REAC:R-HSA-156842 | 0.0279140119136 | 0.666666666667 | RPL28 RPLP0 | Eukaryotic Translation Elongation |
| REAC:R-HSA-2408557 | 0.0279140119136 | 0.666666666667 | RPL28 RPLP0 | Selenocysteine synthesis |
| REAC:R-HSA-975956 | 0.0291450496188 | 0.666666666667 | RPL28 RPLP0 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| REAC:R-HSA-72689 | 0.0329968164925 | 0.666666666667 | RPL28 RPLP0 | Formation of a pool of free 40S subunits |
| REAC:R-HSA-156827 | 0.0399448421955 | 0.666666666667 | RPL28 RPLP0 | L13a-mediated translational silencing of Ceruloplasmin expression |
| REAC:R-HSA-1799339 | 0.0406759452204 | 0.666666666667 | RPL28 RPLP0 | SRP-dependent cotranslational protein targeting to membrane |
| REAC:R-HSA-72706 | 0.0406759452204 | 0.666666666667 | RPL28 RPLP0 | GTP hydrolysis and joining of the 60S ribosomal subunit |
| MIRNA:hsa-miR-382-5p | 0.0420793313921 | 0.666666666667 | RPLP0 YBX1 | hsa-miR-382-5p |
| REAC:R-HSA-975957 | 0.0421579398286 | 0.666666666667 | RPL28 RPLP0 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-927802 | 0.0421579398286 | 0.666666666667 | RPL28 RPLP0 | Nonsense-Mediated Decay (NMD) |
| REAC:R-HSA-2408522 | 0.0429088296136 | 0.666666666667 | RPL28 RPLP0 | Selenoamino acid metabolism |
| REAC:R-HSA-72613 | 0.0459783176444 | 0.666666666667 | RPL28 RPLP0 | Eukaryotic Translation Initiation |
| REAC:R-HSA-72737 | 0.0459783176444 | 0.666666666667 | RPL28 RPLP0 | Cap-dependent Translation Initiation |
| CORUM:2156 | 0.0499776345577 | 0.333333333333 | YBX1 | YBX1-AKT1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPL28 | RPLP0 | 0.999 | 0.948 | hein_WMM bioplex (RPL28,RPLP0) bioplex_WMM boldt Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| YBX1 | RPLP0 | 0.842 | 0.786 | bioplex (RPLP0) bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
| RPL28 | YBX1 | 0.01 | 0.118 | bioplex (RPL28) bioplex_WMM boldt gupta_WMM boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_04416 has an average edge precision of 0.617 which is ranked 1850 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| YBX1 | HuMAP2_01695 HuMAP2_02207 HuMAP2_04416 |
| RPL28 | HuMAP2_01156 HuMAP2_02207 HuMAP2_04416 |
| RPLP0 | HuMAP2_02207 HuMAP2_04416 HuMAP2_04687 HuMAP2_05622 HuMAP2_06551 |