hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04466
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SERPINA1 | Alpha-1-antitrypsin (Alpha-1 protease inhibitor) (Alpha-1-antiproteinase) (Serpin A1) [Cleaved into: Short peptide from AAT (SPAAT)] | UniProt NCBI |
| FBXL5 | F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein) | UniProt NCBI |
| MAPK6 | Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK) | UniProt NCBI |
| ZNF28 | Zinc finger protein 28 (Zinc finger protein KOX24) | UniProt NCBI |
| MAPKAPK5 | MAP kinase-activated protein kinase 5 (MAPK-activated protein kinase 5) (MAPKAP kinase 5) (MAPKAP-K5) (MAPKAPK-5) (MK-5) (MK5) (EC 2.7.11.1) (p38-regulated/activated protein kinase) (PRAK) | UniProt NCBI |
| ZNF7 | Zinc finger protein 7 (Zinc finger protein HF.16) (Zinc finger protein KOX4) | UniProt NCBI |
| APOA1 | Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))] | UniProt NCBI |
| ZNF468 | Zinc finger protein 468 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7548 | 3.50546248845e-05 | 0.25 | MAPKAPK5 MAPK6 | MAPK6-MAPKAPK5-SEPT7 complex |
| CORUM:5388 | 0.0497224828424 | 0.125 | SERPINA1 | SERPINA1-ELA2 complex |
| CORUM:5391 | 0.0497224828424 | 0.125 | SERPINA1 | SERPINA1-CTSG complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAPKAPK5 | MAPK6 | 0.981 | 0.896 | bioplex (MAPK6) bioplex_WMM |
| ZNF468 | MAPK6 | 0.66 | 0.696 | bioplex (MAPK6) bioplex_WMM |
| MAPK6 | FBXL5 | 0.403 | 0.562 | bioplex (FBXL5) bioplex_WMM |
| MAPK6 | ZNF28 | 0.098 | 0.357 | bioplex (MAPK6) bioplex_WMM |
| ZNF7 | MAPK6 | 0.093 | 0.355 | bioplex (MAPK6) bioplex_WMM |
| MAPK6 | SERPINA1 | 0.032 | 0.246 | bioplex (MAPK6) bioplex_WMM |
| MAPK6 | APOA1 | 0.025 | 0.217 | bioplex (MAPK6) bioplex_WMM |
| APOA1 | SERPINA1 | 0.025 | 0.211 | bioplex_WMM WMM_only boldt_WMM treiber_WMM |
| ZNF468 | MAPKAPK5 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| ZNF468 | ZNF28 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| MAPKAPK5 | ZNF28 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| ZNF7 | MAPKAPK5 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| ZNF7 | ZNF468 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| ZNF7 | ZNF28 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| ZNF468 | APOA1 | 0.008 | 0.044 | bioplex_WMM WMM_only |
| MAPKAPK5 | APOA1 | 0.008 | 0.044 | bioplex_WMM WMM_only |
| ZNF468 | SERPINA1 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| MAPKAPK5 | SERPINA1 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| ZNF28 | APOA1 | 0.008 | 0.024 | bioplex_WMM WMM_only |
| ZNF28 | SERPINA1 | 0.008 | 0.01 | bioplex_WMM WMM_only |
| ZNF7 | APOA1 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| ZNF7 | SERPINA1 | 0.007 | 0.016 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04466 has an average edge precision of 0.194 which is ranked 6265 out of all 6965 complexes.
Related Complexes