hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04483
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PLOD1 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1) | UniProt NCBI |
| COL4A1 | Collagen alpha-1(IV) chain [Cleaved into: Arresten] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0025323 | 0.00145265321444 | 1.0 | PLOD1 COL4A1 | Abnormal arterial physiology |
| REAC:R-HSA-1650814 | 0.00316917126735 | 1.0 | PLOD1 COL4A1 | Collagen biosynthesis and modifying enzymes |
| REAC:R-HSA-1474290 | 0.00584226918984 | 1.0 | PLOD1 COL4A1 | Collagen formation |
| HP:0000541 | 0.00901980766025 | 1.0 | PLOD1 COL4A1 | Retinal detachment |
| HP:0000482 | 0.0203872364924 | 1.0 | PLOD1 COL4A1 | Microcornea |
| HP:0001120 | 0.0302051685624 | 1.0 | PLOD1 COL4A1 | Abnormality of corneal size |
| HP:0030163 | 0.0334310605282 | 1.0 | PLOD1 COL4A1 | Abnormal vascular physiology |
| HP:0010727 | 0.0497341708567 | 0.5 | PLOD1 | Spontaneous rupture of the globe |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| COL4A1 | PLOD1 | 0.854 | 0.793 | hein_WMM bioplex (PLOD1) bioplex_WMM |
Images
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Complex HuMAP2_04483 has an average edge precision of 0.793 which is ranked 944 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PLOD1 | HuMAP2_02722 HuMAP2_02856 HuMAP2_04238 HuMAP2_04483 HuMAP2_05080 |
| COL4A1 | HuMAP2_01361 HuMAP2_02856 HuMAP2_04238 HuMAP2_04483 HuMAP2_05080 HuMAP2_05564 |