hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04505
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RSL1D1 | Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1) | UniProt NCBI |
| RRS1 | Ribosome biogenesis regulatory protein homolog | UniProt NCBI |
| BRIX1 | Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2) | UniProt NCBI |
| LLPH | Protein LLP homolog (Protein LAPS18-like) | UniProt NCBI |
| EBNA1BP2 | Probable rRNA-processing protein EBP2 (EBNA1-binding protein 2) (Nucleolar protein p40) | UniProt NCBI |
| NOP56 | Nucleolar protein 56 (Nucleolar protein 5A) | UniProt NCBI |
| DDX24 | ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3055 | 3.79943897204e-06 | 0.571428571429 | RSL1D1 NOP56 EBNA1BP2 BRIX1 | Nop56p-associated pre-rRNA complex |
| GO:0005730 | 3.95971431166e-05 | 1.0 | LLPH RSL1D1 DDX24 NOP56 BRIX1 EBNA1BP2 RRS1 | nucleolus |
| GO:0042273 | 0.000503784351922 | 0.571428571429 | RSL1D1 RRS1 EBNA1BP2 BRIX1 | ribosomal large subunit biogenesis |
| GO:0030684 | 0.000919053594983 | 0.571428571429 | RSL1D1 NOP56 RRS1 EBNA1BP2 | preribosome |
| GO:0042254 | 0.000959205344393 | 0.714285714286 | RSL1D1 NOP56 RRS1 EBNA1BP2 BRIX1 | ribosome biogenesis |
| GO:0003723 | 0.00369263749287 | 1.0 | LLPH RSL1D1 DDX24 NOP56 BRIX1 EBNA1BP2 RRS1 | RNA binding |
| GO:0022613 | 0.00928376179311 | 0.714285714286 | RSL1D1 NOP56 RRS1 EBNA1BP2 BRIX1 | ribonucleoprotein complex biogenesis |
| MIRNA:hsa-miR-6500-3p | 0.0196293825519 | 0.428571428571 | BRIX1 RRS1 EBNA1BP2 | hsa-miR-6500-3p |
| MIRNA:hsa-miR-3614-5p | 0.0225609609452 | 0.428571428571 | BRIX1 RRS1 EBNA1BP2 | hsa-miR-3614-5p |
| GO:0006364 | 0.0299438047992 | 0.571428571429 | RSL1D1 NOP56 RRS1 EBNA1BP2 | rRNA processing |
| GO:0016072 | 0.0366882871231 | 0.571428571429 | RSL1D1 NOP56 RRS1 EBNA1BP2 | rRNA metabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BRIX1 | EBNA1BP2 | 1.0 | 0.949 | hein_WMM bioplex (EBNA1BP2) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| RRS1 | EBNA1BP2 | 0.999 | 0.949 | bioplex (EBNA1BP2,RRS1) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| EBNA1BP2 | LLPH | 0.979 | 0.895 | bioplex_WMM youn_WMM fraction treiber_WMM |
| RRS1 | BRIX1 | 0.973 | 0.886 | bioplex (RRS1) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| EBNA1BP2 | NOP56 | 0.968 | 0.88 | hein_WMM bioplex_WMM Guru youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| BRIX1 | LLPH | 0.958 | 0.863 | bioplex_WMM youn_WMM fraction |
| BRIX1 | NOP56 | 0.956 | 0.862 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| RRS1 | DDX24 | 0.943 | 0.856 | bioplex (RRS1) bioplex_WMM youn_WMM gupta_WMM fraction |
| NOP56 | RSL1D1 | 0.942 | 0.856 | hein_WMM bioplex_WMM youn_WMM hein (NOP56) gupta_WMM treiber_WMM |
| EBNA1BP2 | DDX24 | 0.932 | 0.846 | hein_WMM bioplex (EBNA1BP2) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| EBNA1BP2 | RSL1D1 | 0.825 | 0.774 | hein_WMM bioplex (EBNA1BP2) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| NOP56 | DDX24 | 0.809 | 0.77 | hein_WMM bioplex_WMM Guru youn_WMM hein (NOP56) gupta_WMM fraction treiber_WMM |
| RRS1 | LLPH | 0.463 | 0.6 | bioplex_WMM youn_WMM fraction treiber_WMM |
| BRIX1 | DDX24 | 0.448 | 0.592 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| RRS1 | RSL1D1 | 0.103 | 0.366 | bioplex (RRS1) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| BRIX1 | RSL1D1 | 0.047 | 0.29 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| RRS1 | NOP56 | 0.03 | 0.238 | bioplex (RRS1) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| LLPH | DDX24 | 0.014 | 0.136 | bioplex_WMM youn_WMM WMM_only |
| LLPH | RSL1D1 | 0.013 | 0.15 | bioplex_WMM youn_WMM WMM_only |
| DDX24 | RSL1D1 | 0.005 | 0.012 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| NOP56 | LLPH | 0.003 | 0.015 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_04505 has an average edge precision of 0.609 which is ranked 1901 out of all 6965 complexes.
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