hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04515
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NAA15 | N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gastric cancer antigen Ga19) (N-terminal acetyltransferase) (NMDA receptor-regulated protein 1) (Protein tubedown-1) (Tbdn100) | UniProt NCBI |
| NAA50 | N-alpha-acetyltransferase 50 (hNaa50p) (EC 2.3.1.258) (N-acetyltransferase 13) (N-acetyltransferase 5) (hNAT5) (N-acetyltransferase san homolog) (hSAN) (N-epsilon-acetyltransferase 50) (EC 2.3.1.-) (NatE catalytic subunit) | UniProt NCBI |
| NAA10 | N-alpha-acetyltransferase 10 (EC 2.3.1.255) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (hARD1) (NatA catalytic subunit Naa10) | UniProt NCBI |
| NAA11 | N-alpha-acetyltransferase 11 (EC 2.3.1.255) (N-terminal acetyltransferase complex ARD1 subunit homolog B) (hARD2) (NatA catalytic subunit Naa11) | UniProt NCBI |
| NAA16 | N-alpha-acetyltransferase 16, NatA auxiliary subunit (NMDA receptor-regulated 1-like protein) (NARG1-like protein) | UniProt NCBI |
| HYPK | Huntingtin-interacting protein K (Huntingtin yeast partner K) | UniProt NCBI |
| HNRNPL | Heterogeneous nuclear ribonucleoprotein L (hnRNP L) | UniProt NCBI |
| MANF | Mesencephalic astrocyte-derived neurotrophic factor (Arginine-rich protein) (Protein ARMET) | UniProt NCBI |
| ZYG11B | Protein zyg-11 homolog B | UniProt NCBI |
| RIN2 | Ras and Rab interactor 2 (Ras association domain family 4) (Ras inhibitor JC265) (Ras interaction/interference protein 2) | UniProt NCBI |
| TOMM34 | Mitochondrial import receptor subunit TOM34 (hTom34) (Translocase of outer membrane 34 kDa subunit) | UniProt NCBI |
| TSGA10IP | Testis-specific protein 10-interacting protein (Tsga10-interacting protein) | UniProt NCBI |
| PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-3) (Phospholipase C-beta-3) (PLC-beta-3) | UniProt NCBI |
| SH3BGRL | SH3 domain-binding glutamic acid-rich-like protein | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0031415 | 1.64002397e-11 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | NatA complex |
| GO:0031414 | 4.12246081009e-09 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | N-terminal protein acetyltransferase complex |
| GO:0004596 | 1.29432526962e-08 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | peptide alpha-N-acetyltransferase activity |
| GO:0006474 | 1.00872787508e-07 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | N-terminal protein amino acid acetylation |
| GO:0031365 | 1.30938963319e-06 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | N-terminal protein amino acid modification |
| GO:0034212 | 0.000153510037254 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | peptide N-acetyltransferase activity |
| GO:0008080 | 0.000312471073581 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | N-acetyltransferase activity |
| GO:0031248 | 0.00061613120339 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | protein acetyltransferase complex |
| GO:1902493 | 0.00061613120339 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | acetyltransferase complex |
| GO:0016410 | 0.00069050731922 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | N-acyltransferase activity |
| GO:0016407 | 0.000957438682099 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | acetyltransferase activity |
| GO:0006473 | 0.00815151581613 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | protein acetylation |
| GO:0043543 | 0.0236094431448 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | protein acylation |
| GO:0016747 | 0.024925312992 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | transferase activity, transferring acyl groups other than amino-acyl groups |
| GO:1990190 | 0.0410249304355 | 0.142857142857 | NAA10 NAA11 | peptide-glutamate-N-acetyltransferase activity |
| GO:0017198 | 0.0410249304355 | 0.142857142857 | NAA10 NAA11 | N-terminal peptidyl-serine acetylation |
| GO:0030920 | 0.0410249304355 | 0.142857142857 | NAA10 NAA11 | peptidyl-serine acetylation |
| GO:0051604 | 0.0425739468458 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | protein maturation |
| GO:0016746 | 0.0446675995009 | 0.357142857143 | NAA10 NAA15 NAA16 NAA50 NAA11 | transferase activity, transferring acyl groups |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NAA15 | NAA10 | 1.0 | 0.949 | hein_WMM bioplex (NAA15) bioplex_WMM youn_WMM hein (NAA10,NAA15) gupta_WMM fraction |
| NAA15 | HYPK | 1.0 | 0.949 | hein_WMM bioplex (NAA15) bioplex_WMM Guru youn_WMM hein (NAA15) gupta_WMM fraction |
| NAA16 | NAA10 | 1.0 | 0.949 | hein_WMM bioplex_WMM hein (NAA10) fraction |
| NAA11 | RIN2 | 1.0 | 0.949 | bioplex (RIN2) bioplex_WMM |
| NAA16 | TSGA10IP | 0.998 | 0.937 | bioplex (TSGA10IP) bioplex_WMM |
| NAA15 | NAA11 | 0.997 | 0.934 | hein_WMM hein (NAA11) fraction |
| NAA16 | NAA11 | 0.997 | 0.93 | hein_WMM hein (NAA11) fraction |
| NAA15 | NAA50 | 0.994 | 0.923 | hein_WMM bioplex (NAA15) bioplex_WMM youn_WMM hein (NAA15,NAA50) gupta_WMM |
| HYPK | NAA10 | 0.993 | 0.918 | hein_WMM bioplex_WMM youn_WMM hein (NAA10) gupta_WMM fraction |
| NAA16 | NAA15 | 0.936 | 0.85 | hein_WMM bioplex (NAA15) bioplex_WMM |
| NAA11 | HYPK | 0.898 | 0.823 | hein_WMM hein (NAA11) fraction |
| NAA50 | HNRNPL | 0.598 | 0.668 | bioplex_WMM youn_WMM gupta_WMM fraction |
| NAA16 | HYPK | 0.306 | 0.501 | hein_WMM bioplex_WMM Guru fraction |
| NAA15 | MANF | 0.171 | 0.43 | bioplex_WMM fraction |
| MANF | NAA10 | 0.111 | 0.379 | fraction |
| HYPK | NAA50 | 0.091 | 0.354 | hein_WMM bioplex_WMM hein (NAA50) |
| NAA11 | NAA50 | 0.077 | 0.352 | hein_WMM hein (NAA11) |
| NAA16 | NAA50 | 0.064 | 0.348 | hein_WMM bioplex_WMM hein (NAA50) |
| HYPK | TSGA10IP | 0.036 | 0.263 | bioplex (TSGA10IP) bioplex_WMM |
| HYPK | PLCB3 | 0.035 | 0.263 | fraction |
| HNRNPL | TOMM34 | 0.032 | 0.241 | bioplex_WMM fraction treiber_WMM |
| TSGA10IP | ZYG11B | 0.029 | 0.231 | bioplex (TSGA10IP) bioplex_WMM |
| SH3BGRL | HNRNPL | 0.028 | 0.232 | bioplex_WMM fraction |
| NAA50 | TOMM34 | 0.025 | 0.211 | bioplex_WMM fraction |
| NAA50 | TSGA10IP | 0.021 | 0.184 | bioplex (TSGA10IP) bioplex_WMM |
| TSGA10IP | NAA10 | 0.015 | 0.145 | bioplex (TSGA10IP) bioplex_WMM |
| NAA50 | NAA10 | 0.011 | 0.145 | hein_WMM bioplex_WMM youn_WMM hein (NAA10,NAA50) gupta_WMM fraction |
| NAA10 | PLCB3 | 0.009 | 0.114 | fraction |
| RIN2 | NAA10 | 0.009 | 0.097 | bioplex (RIN2) bioplex_WMM |
| NAA15 | TOMM34 | 0.008 | 0.096 | bioplex_WMM WMM_only |
| NAA11 | NAA10 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| NAA10 | HNRNPL | 0.007 | 0.01 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ZYG11B | SH3BGRL | 0.007 | 0.005 | bioplex_WMM WMM_only |
| NAA15 | HNRNPL | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| NAA16 | ZYG11B | 0.007 | 0.0 | bioplex_WMM WMM_only |
| HYPK | ZYG11B | 0.007 | 0.003 | bioplex_WMM WMM_only |
| MANF | SH3BGRL | 0.007 | 0.0 | bioplex_WMM WMM_only treiber_WMM |
| ZYG11B | HNRNPL | 0.007 | 0.002 | bioplex_WMM WMM_only |
| NAA15 | SH3BGRL | 0.007 | 0.002 | bioplex_WMM WMM_only |
| NAA10 | SH3BGRL | 0.007 | 0.001 | bioplex_WMM WMM_only |
| SH3BGRL | TOMM34 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| MANF | HNRNPL | 0.007 | 0.001 | gupta_WMM WMM_only |
| NAA50 | MANF | 0.007 | 0.001 | bioplex_WMM WMM_only |
| MANF | TOMM34 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| NAA10 | TOMM34 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| NAA50 | SH3BGRL | 0.007 | 0.001 | bioplex_WMM WMM_only |
| HYPK | HNRNPL | 0.007 | 0.007 | youn_WMM gupta_WMM fraction |
| MANF | ZYG11B | 0.007 | 0.005 | bioplex_WMM WMM_only |
| NAA50 | ZYG11B | 0.007 | 0.004 | bioplex_WMM WMM_only |
| RIN2 | HNRNPL | 0.006 | 0.006 | bioplex (RIN2) |
| NAA10 | ZYG11B | 0.006 | 0.003 | bioplex_WMM WMM_only |
| NAA15 | PLCB3 | 0.004 | 0.015 | fraction |
| NAA11 | MANF | 0.0 | 0.007 | fraction |
| HYPK | MANF | 0.0 | 0.001 | fraction |
| NAA16 | MANF | 0.0 | 0.0 | fraction |
| MANF | PLCB3 | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_04515 has an average edge precision of 0.277 which is ranked 4925 out of all 6965 complexes.
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