hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04523
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ABCB6 | ATP-binding cassette sub-family B member 6, mitochondrial (Mitochondrial ABC transporter 3) (Mt-ABC transporter 3) (P-glycoprotein-related protein) (Ubiquitously-expressed mammalian ABC half transporter) | UniProt NCBI |
| TEX2 | Testis-expressed protein 2 (Transmembrane protein 96) | UniProt NCBI |
| MRAP2 | Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2) | UniProt NCBI |
| SLC25A38 | Mitochondrial glycine transporter (Mitochondrial glycine transporter GlyC) (Solute carrier family 25 member 38) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0025065 | 0.0038810174634 | 0.5 | ABCB6 SLC25A38 | Abnormal mean corpuscular volume |
| REAC:R-HSA-5683371 | 0.0499190562503 | 0.25 | ABCB6 | Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MRAP2 | SLC25A38 | 0.057 | 0.324 | bioplex (MRAP2) bioplex_WMM |
| MRAP2 | ABCB6 | 0.022 | 0.2 | bioplex (MRAP2) bioplex_WMM |
| TEX2 | MRAP2 | 0.021 | 0.185 | bioplex (MRAP2) bioplex_WMM |
| TEX2 | SLC25A38 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| SLC25A38 | ABCB6 | 0.007 | 0.011 | bioplex_WMM WMM_only |
| TEX2 | ABCB6 | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_04523 has an average edge precision of 0.135 which is ranked 6802 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ABCB6 | HuMAP2_04523 |
| TEX2 | HuMAP2_03152 HuMAP2_04523 HuMAP2_05342 |
| MRAP2 | HuMAP2_03287 HuMAP2_04300 HuMAP2_04523 HuMAP2_06592 |
| SLC25A38 | HuMAP2_04300 HuMAP2_04523 HuMAP2_06592 |