hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04524
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RPL9 | 60S ribosomal protein L9 (Large ribosomal subunit protein uL6) | UniProt NCBI |
| CGNL1 | Cingulin-like protein 1 (Junction-associated coiled-coil protein) (Paracingulin) | UniProt NCBI |
| CGN | Cingulin | UniProt NCBI |
| LMNB2 | Lamin-B2 | UniProt NCBI |
| RRP7A | Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14) | UniProt NCBI |
| NOL6 | Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6791226 | 0.00563418329838 | 0.5 | NOL6 RRP7A RPL9 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.00661628360681 | 0.5 | NOL6 RRP7A RPL9 | rRNA processing in the nucleus and cytosol |
| GO:0032545 | 0.00676235117068 | 0.333333333333 | NOL6 RRP7A | CURI complex |
| GO:0034456 | 0.00676235117068 | 0.333333333333 | NOL6 RRP7A | UTP-C complex |
| REAC:R-HSA-72312 | 0.00770517770968 | 0.5 | NOL6 RRP7A RPL9 | rRNA processing |
| KEGG:03008 | 0.0180762834417 | 0.333333333333 | NOL6 RRP7A | Ribosome biogenesis in eukaryotes |
| MIRNA:hsa-miR-3158-3p | 0.0371299472089 | 0.333333333333 | LMNB2 RRP7A | hsa-miR-3158-3p |
| REAC:R-HSA-6790901 | 0.0388379782234 | 0.333333333333 | NOL6 RRP7A | rRNA modification in the nucleus and cytosol |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RRP7A | NOL6 | 0.971 | 0.882 | bioplex (RRP7A) bioplex_WMM youn_WMM gupta_WMM fraction |
| NOL6 | RPL9 | 0.179 | 0.438 | hein_WMM bioplex_WMM gupta_WMM fraction treiber_WMM |
| RPL9 | CGN | 0.117 | 0.389 | gupta_WMM fraction |
| RRP7A | RPL9 | 0.083 | 0.35 | bioplex_WMM Malo gupta_WMM fraction treiber_WMM |
| RPL9 | CGNL1 | 0.077 | 0.352 | gupta_WMM fraction |
| LMNB2 | RRP7A | 0.077 | 0.354 | gupta_WMM fraction |
| LMNB2 | NOL6 | 0.07 | 0.348 | Guru youn_WMM gupta_WMM fraction treiber_WMM |
| CGN | CGNL1 | 0.007 | 0.005 | youn_WMM WMM_only |
| NOL6 | CGN | 0.007 | 0.005 | youn_WMM gupta_WMM WMM_only |
| RRP7A | CGN | 0.007 | 0.001 | youn_WMM gupta_WMM WMM_only |
| NOL6 | CGNL1 | 0.007 | 0.003 | youn_WMM WMM_only |
| RRP7A | CGNL1 | 0.007 | 0.002 | youn_WMM WMM_only |
| LMNB2 | CGNL1 | 0.0 | 0.015 | fraction |
| LMNB2 | RPL9 | 0.0 | 0.012 | bioplex_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_04524 has an average edge precision of 0.225 which is ranked 5769 out of all 6965 complexes.
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