hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_04530
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BBS9 | Protein PTHB1 (Bardet-Biedl syndrome 9 protein) (Parathyroid hormone-responsive B1 gene protein) | UniProt NCBI |
| BBS1 | Bardet-Biedl syndrome 1 protein (BBS2-like protein 2) | UniProt NCBI |
| BBS7 | Bardet-Biedl syndrome 7 protein (BBS2-like protein 1) | UniProt NCBI |
| TTC8 | Tetratricopeptide repeat protein 8 (TPR repeat protein 8) (Bardet-Biedl syndrome 8 protein) | UniProt NCBI |
| BBS10 | Bardet-Biedl syndrome 10 protein | UniProt NCBI |
| BBS4 | Bardet-Biedl syndrome 4 protein | UniProt NCBI |
| BBS2 | Bardet-Biedl syndrome 2 protein | UniProt NCBI |
| BBS5 | Bardet-Biedl syndrome 5 protein | UniProt NCBI |
| LZTFL1 | Leucine zipper transcription factor-like protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5620922 | 5.90542297556e-25 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | BBSome-mediated cargo-targeting to cilium |
| HP:0010747 | 1.43090688041e-23 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Medial flaring of the eyebrow |
| CORUM:6163 | 3.69393785629e-22 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | BBSome |
| REAC:R-HSA-5620920 | 2.73773332715e-21 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Cargo trafficking to the periciliary membrane |
| HP:0008724 | 3.10391772782e-20 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hypoplasia of the ovary |
| HP:0010462 | 4.4534471747e-20 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Aplasia/Hypoplasia of the ovary |
| GO:0034464 | 4.46966480611e-19 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | BBSome |
| WP:WP4536 | 1.51571629981e-18 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Genes related to primary cilium development (based on CRISPR) |
| HP:0001162 | 3.59248732439e-18 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Postaxial hand polydactyly |
| HP:0000003 | 8.22968769875e-18 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Multicystic kidney dysplasia |
| HP:0002230 | 1.21242016682e-17 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Generalized hirsutism |
| HP:0001395 | 1.21242016682e-17 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hepatic fibrosis |
| HP:0031065 | 1.21242016682e-17 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal ovarian morphology |
| HP:0000100 | 2.73955544214e-17 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Nephrotic syndrome |
| HP:0100259 | 5.33959541345e-17 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Postaxial polydactyly |
| HP:0000580 | 3.27624223956e-16 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Pigmentary retinopathy |
| HP:0000512 | 5.46106631207e-16 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal electroretinogram |
| HP:0001161 | 6.56667843665e-16 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hand polydactyly |
| HP:0001007 | 9.39122549745e-16 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hirsutism |
| HP:0000426 | 1.11725795984e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Prominent nasal bridge |
| HP:0006101 | 1.1829790163e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Finger syndactyly |
| REAC:R-HSA-5617833 | 1.54684171442e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Cilium Assembly |
| HP:0009997 | 2.28651819964e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Duplication of phalanx of hand |
| HP:0004275 | 2.41048605384e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Duplication of hand bones |
| HP:0009142 | 2.41048605384e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Duplication of bones involving the upper extremities |
| HP:0000137 | 4.02063543272e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the ovary |
| HP:0030453 | 4.43870188602e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal visual electrophysiology |
| HP:0000368 | 6.52421694791e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Low-set, posteriorly rotated ears |
| HP:0010442 | 8.61877522264e-15 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Polydactyly |
| HP:0000107 | 1.12910262756e-14 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Renal cyst |
| HP:0000556 | 4.55080701506e-14 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Retinal dystrophy |
| REAC:R-HSA-1852241 | 4.97812744485e-14 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Organelle biogenesis and maintenance |
| HP:0000470 | 6.36481718644e-14 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Short neck |
| HP:0000822 | 7.09854355912e-14 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hypertension |
| GO:0001103 | 8.69868923753e-14 | 0.777777777778 | BBS5 BBS7 BBS2 BBS4 BBS1 TTC8 BBS10 | RNA polymerase II repressing transcription factor binding |
| WP:WP4656 | 1.0819011031e-13 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | Joubert Syndrome |
| HP:0007703 | 1.37599551647e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of retinal pigmentation |
| HP:0003319 | 1.7354305398e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the cervical spine |
| HP:0032263 | 1.97631299427e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Increased blood pressure |
| HP:0000135 | 2.97768075154e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hypogonadism |
| HP:0000358 | 3.26462804286e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Posteriorly rotated ears |
| HP:0001159 | 3.26462804286e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Syndactyly |
| HP:0000510 | 3.27402523354e-13 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | Rod-cone dystrophy |
| HP:0001513 | 4.27864791229e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Obesity |
| HP:0004207 | 5.8918130393e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal 5th finger morphology |
| WP:WP4352 | 7.86262676362e-13 | 0.888888888889 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Ciliary landscape |
| HP:0030972 | 8.95552599755e-13 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal systemic blood pressure |
| HP:0004324 | 1.08178179122e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Increased body weight |
| HP:0008736 | 1.17160934851e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hypoplasia of penis |
| HP:0000494 | 1.37139114046e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Downslanted palpebral fissures |
| CORUM:6165 | 2.54036423996e-12 | 0.444444444444 | BBS1 BBS7 BBS9 BBS2 | BBSome core complex |
| HP:0000534 | 3.5862779827e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal eyebrow morphology |
| HP:0000050 | 4.21769430283e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hypoplastic male external genitalia |
| HP:0003202 | 5.65719385514e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Skeletal muscle atrophy |
| HP:0000464 | 6.45779941535e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the neck |
| HP:0003241 | 6.45779941535e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | External genital hypoplasia |
| HP:0000008 | 8.36711571504e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of female internal genitalia |
| HP:0000080 | 9.9039987873e-12 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of reproductive system physiology |
| CORUM:6601 | 1.26984090249e-11 | 0.444444444444 | BBS5 BBS1 BBS4 TTC8 | BBS1-BBS4-BBS5-PKD1-TTC8 complex |
| HP:0000812 | 1.61296491729e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal internal genitalia |
| HP:0011362 | 1.92391816145e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal hair quantity |
| GO:0070491 | 2.42231673569e-11 | 0.777777777778 | BBS5 BBS7 BBS2 BBS4 BBS1 TTC8 BBS10 | repressing transcription factor binding |
| HP:0010460 | 2.51408138246e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the female genitalia |
| HP:0200006 | 3.02906765604e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Slanting of the palpebral fissure |
| HP:0005918 | 4.04956917793e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal finger phalanx morphology |
| HP:0012211 | 4.12246142313e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal renal physiology |
| HP:0030236 | 4.74888950042e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of muscle size |
| HP:0008373 | 5.18208541635e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Puberty and gonadal disorders |
| HP:0000036 | 5.36496873001e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the penis |
| HP:0000369 | 5.74803518646e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Low-set ears |
| HP:0000028 | 6.26094337893e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Cryptorchidism |
| HP:0000357 | 9.79977860675e-11 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal location of ears |
| HP:0008050 | 1.02860791606e-10 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the palpebral fissures |
| HP:0410042 | 3.7289915629e-10 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal liver morphology |
| HP:0000479 | 5.25084848692e-10 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal retinal morphology |
| HP:0000035 | 5.68953847995e-10 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal testis morphology |
| HP:0000422 | 9.54502506105e-10 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the nasal bridge |
| HP:0012210 | 9.91105981791e-10 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal renal morphology |
| HP:0000639 | 1.5202131406e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Nystagmus |
| HP:0012547 | 1.71160360523e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal involuntary eye movements |
| HP:0011277 | 1.8150989809e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the urinary system physiology |
| HP:0001392 | 2.42074554995e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the liver |
| HP:0000032 | 2.42074554995e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of male external genitalia |
| HP:0001167 | 3.16479474135e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of finger |
| HP:0010461 | 3.27080287911e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the male genitalia |
| HP:0000811 | 3.30683375538e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal external genitalia |
| HP:0000356 | 3.56908674587e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the outer ear |
| HP:0001595 | 4.61433011099e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal hair morphology |
| HP:0002167 | 5.28723899734e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Neurological speech impairment |
| HP:0000492 | 5.98437815248e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal eyelid morphology |
| HP:0011025 | 7.70475904462e-09 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal cardiovascular system physiology |
| HP:0001098 | 1.01418546947e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal fundus morphology |
| HP:0004329 | 1.04398014153e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal posterior eye segment morphology |
| HP:0002012 | 1.06427302325e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the abdominal organs |
| HP:0000077 | 1.14899625987e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the kidney |
| HP:0011138 | 1.41372670704e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of skin adnexa morphology |
| HP:0010935 | 1.48096412168e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the upper urinary tract |
| HP:0000818 | 1.60918657976e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the endocrine system |
| HP:0004322 | 1.60918657976e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Short stature |
| GO:0060271 | 1.83937185998e-08 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | cilium assembly |
| HP:0011297 | 1.87857528463e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal digit morphology |
| HP:0012243 | 2.14880585005e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal reproductive system morphology |
| HP:0030669 | 2.36839175583e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal ocular adnexa morphology |
| HP:0032039 | 2.72341073971e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the ocular adnexa |
| GO:0044782 | 2.79258313883e-08 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | cilium organization |
| HP:0001155 | 2.8436609952e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the hand |
| HP:0000925 | 2.8436609952e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the vertebral column |
| HP:0000002 | 2.96860791126e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of body height |
| HP:0000315 | 3.17869245504e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the orbital region |
| HP:0000365 | 3.70041293878e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hearing impairment |
| HP:0000364 | 4.1574326114e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Hearing abnormality |
| HP:0031704 | 4.1574326114e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal ear physiology |
| HP:0002817 | 5.93805650753e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the upper limb |
| HP:0000078 | 6.08107238844e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the genital system |
| HP:0040068 | 6.52867017816e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of limb bone |
| HP:0002813 | 6.52867017816e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of limb bone morphology |
| HP:0000496 | 9.4480052429e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of eye movement |
| HP:0000366 | 9.88436722205e-08 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the nose |
| HP:0004323 | 1.03385524694e-07 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of body weight |
| HP:0011844 | 1.27128934261e-07 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal appendicular skeleton morphology |
| HP:0001510 | 1.75531471746e-07 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Growth delay |
| HP:0011805 | 2.06097753729e-07 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal skeletal muscle morphology |
| GO:0120031 | 2.71334139071e-07 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | plasma membrane bounded cell projection assembly |
| GO:0061629 | 2.7814939594e-07 | 0.777777777778 | BBS5 BBS7 BBS2 BBS4 BBS1 TTC8 BBS10 | RNA polymerase II-specific DNA-binding transcription factor binding |
| GO:0030031 | 3.18468288789e-07 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | cell projection assembly |
| GO:0036064 | 3.67242223947e-07 | 0.666666666667 | BBS5 BBS7 BBS2 BBS1 TTC8 BBS4 | ciliary basal body |
| HP:0000079 | 3.93679828805e-07 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the urinary system |
| HP:0031703 | 4.8872673273e-07 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal ear morphology |
| HP:0001249 | 4.8872673273e-07 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Intellectual disability |
| HP:0040064 | 1.21855040875e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of limbs |
| HP:0000598 | 1.23245892616e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the ear |
| GO:0140297 | 1.52112356035e-06 | 0.777777777778 | BBS5 BBS7 BBS2 BBS4 BBS1 TTC8 BBS10 | DNA-binding transcription factor binding |
| HP:0012372 | 2.58314268072e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal eye morphology |
| HP:0012373 | 3.17579094274e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal eye physiology |
| GO:0044441 | 4.17519876399e-06 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | ciliary part |
| HP:0001574 | 4.31325244036e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the integument |
| HP:0000119 | 4.53080525311e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the genitourinary system |
| HP:0001507 | 4.71181336473e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Growth abnormality |
| HP:0001626 | 5.21791772653e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the cardiovascular system |
| HP:0009121 | 5.68958728594e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormal axial skeleton morphology |
| HP:0011446 | 6.74808831009e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of higher mental function |
| GO:0070925 | 7.56682579744e-06 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | organelle assembly |
| GO:0051904 | 9.37062910447e-06 | 0.444444444444 | BBS5 BBS2 BBS4 BBS7 | pigment granule transport |
| GO:0032402 | 9.37062910447e-06 | 0.444444444444 | BBS5 BBS2 BBS4 BBS7 | melanosome transport |
| HP:0012759 | 9.40361936555e-06 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Neurodevelopmental abnormality |
| HP:0025031 | 1.12991680139e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the digestive system |
| HP:0000546 | 1.1358198726e-05 | 0.555555555556 | TTC8 BBS1 BBS4 LZTFL1 BBS2 | Retinal degeneration |
| GO:0051905 | 1.18662729599e-05 | 0.444444444444 | BBS5 BBS2 BBS4 BBS7 | establishment of pigment granule localization |
| GO:0032401 | 1.18662729599e-05 | 0.444444444444 | BBS5 BBS2 BBS4 BBS7 | establishment of melanosome localization |
| HP:0003011 | 1.2504972472e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the musculature |
| HP:0000271 | 1.31210764268e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the face |
| GO:0005929 | 1.82513171222e-05 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | cilium |
| GO:0051875 | 1.8313071555e-05 | 0.444444444444 | BBS5 BBS2 BBS4 BBS7 | pigment granule localization |
| GO:0032400 | 1.8313071555e-05 | 0.444444444444 | BBS5 BBS2 BBS4 BBS7 | melanosome localization |
| HP:0000478 | 2.11986595024e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the eye |
| HP:0011842 | 2.30172322517e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of skeletal morphology |
| HP:0000007 | 2.32065006201e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Autosomal recessive inheritance |
| HP:0000924 | 3.11356334818e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the skeletal system |
| HP:0000234 | 3.18835193815e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the head |
| HP:0000152 | 3.38235588648e-05 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of head or neck |
| CORUM:6166 | 4.02261743042e-05 | 0.222222222222 | TTC8 BBS4 | BBSome linker complex |
| GO:0045494 | 4.56829686442e-05 | 0.444444444444 | BBS10 BBS1 BBS4 BBS2 | photoreceptor cell maintenance |
| GO:1905515 | 9.60189204298e-05 | 0.444444444444 | BBS10 BBS1 BBS4 TTC8 | non-motile cilium assembly |
| GO:0008134 | 0.000107167136893 | 0.777777777778 | BBS5 BBS7 BBS2 BBS4 BBS1 TTC8 BBS10 | transcription factor binding |
| HP:0012638 | 0.000115006941524 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of nervous system physiology |
| GO:0120036 | 0.000184350691284 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | plasma membrane bounded cell projection organization |
| GO:0030030 | 0.000200958578249 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | cell projection organization |
| HP:0000707 | 0.000208148186959 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Abnormality of the nervous system |
| GO:0005815 | 0.000272713524189 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | microtubule organizing center |
| GO:0061512 | 0.000375385245224 | 0.444444444444 | BBS1 BBS9 LZTFL1 BBS4 | protein localization to cilium |
| GO:0033059 | 0.000375385245224 | 0.444444444444 | BBS5 BBS2 BBS4 BBS7 | cellular pigmentation |
| CORUM:6247 | 0.000602070214397 | 0.222222222222 | BBS7 BBS10 | BBS-chaperonin complex |
| GO:0001895 | 0.00111330974298 | 0.444444444444 | BBS10 BBS1 BBS4 BBS2 | retina homeostasis |
| HP:0000005 | 0.00113822539788 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Mode of inheritance |
| GO:0043473 | 0.00137843937587 | 0.444444444444 | BBS5 BBS2 BBS4 BBS7 | pigmentation |
| GO:0044463 | 0.0016968385817 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | cell projection part |
| GO:0120038 | 0.0016968385817 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | plasma membrane bounded cell projection part |
| HP:0000118 | 0.00215984608374 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | Phenotypic abnormality |
| HP:0000001 | 0.00218670209197 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | HP root |
| CORUM:0000000 | 0.00227951320903 | 0.888888888889 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 | CORUM root |
| WP:000000 | 0.00566194757866 | 1.0 | BBS5 BBS7 BBS2 BBS10 BBS1 BBS9 TTC8 BBS4 LZTFL1 | WIKIPATHWAYS |
| GO:0015630 | 0.00596473115646 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | microtubule cytoskeleton |
| HP:0001156 | 0.00741175976134 | 0.444444444444 | BBS1 BBS4 LZTFL1 BBS5 | Brachydactyly |
| GO:0001894 | 0.015428956119 | 0.444444444444 | BBS10 BBS1 BBS4 BBS2 | tissue homeostasis |
| GO:0045444 | 0.016018053404 | 0.444444444444 | BBS2 BBS7 BBS9 BBS4 | fat cell differentiation |
| GO:0120025 | 0.0253494187895 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | plasma membrane bounded cell projection |
| GO:0042995 | 0.0269022091829 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | cell projection |
| GO:0044430 | 0.0316875099411 | 0.777777777778 | BBS5 BBS7 BBS2 BBS1 BBS9 TTC8 BBS4 | cytoskeletal part |
| HP:0011927 | 0.0406874986654 | 0.444444444444 | BBS1 BBS4 LZTFL1 BBS5 | Short digit |
| GO:0038108 | 0.0486736709081 | 0.222222222222 | BBS2 BBS4 | negative regulation of appetite by leptin-mediated signaling pathway |
| GO:0050893 | 0.0486736709081 | 0.222222222222 | TTC8 BBS4 | sensory processing |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BBS1 | BBS5 | 0.997 | 0.93 | bioplex (BBS1,BBS5) bioplex_WMM boldt (BBS1,BBS5) boldt_WMM |
| BBS9 | BBS5 | 0.996 | 0.928 | bioplex (BBS5) bioplex_WMM boldt (BBS5,BBS9) boldt_WMM |
| BBS4 | BBS5 | 0.995 | 0.924 | bioplex (BBS5) bioplex_WMM boldt (BBS4,BBS5) boldt_WMM |
| BBS9 | BBS1 | 0.992 | 0.912 | bioplex (BBS1) bioplex_WMM boldt (BBS1,BBS9) boldt_WMM |
| TTC8 | BBS5 | 0.986 | 0.9 | bioplex (BBS5) bioplex_WMM boldt (BBS5,TTC8) boldt_WMM |
| BBS4 | BBS1 | 0.979 | 0.895 | bioplex (BBS1) bioplex_WMM boldt (BBS1,BBS4) boldt_WMM |
| BBS2 | BBS7 | 0.976 | 0.891 | bioplex (BBS7) bioplex_WMM boldt (BBS2,BBS7) boldt_WMM |
| BBS1 | TTC8 | 0.973 | 0.886 | bioplex (BBS1) bioplex_WMM boldt (BBS1,TTC8) boldt_WMM |
| BBS2 | BBS5 | 0.948 | 0.857 | bioplex (BBS5) bioplex_WMM boldt (BBS2,BBS5) boldt_WMM |
| BBS9 | BBS7 | 0.858 | 0.795 | bioplex (BBS7) bioplex_WMM boldt (BBS9) boldt_WMM |
| BBS7 | BBS5 | 0.823 | 0.774 | bioplex (BBS5,BBS7) bioplex_WMM boldt (BBS5) boldt_WMM |
| BBS1 | BBS2 | 0.699 | 0.721 | bioplex (BBS1) bioplex_WMM boldt (BBS1,BBS2) boldt_WMM |
| BBS1 | BBS7 | 0.444 | 0.587 | bioplex (BBS1,BBS7) bioplex_WMM boldt (BBS1) boldt_WMM |
| BBS4 | BBS7 | 0.324 | 0.513 | bioplex (BBS7) bioplex_WMM boldt (BBS4) boldt_WMM |
| BBS4 | LZTFL1 | 0.181 | 0.436 | bioplex (LZTFL1) bioplex_WMM |
| BBS7 | TTC8 | 0.169 | 0.426 | bioplex (BBS7) bioplex_WMM boldt (TTC8) boldt_WMM |
| BBS9 | TTC8 | 0.146 | 0.409 | bioplex_WMM boldt (BBS9,TTC8) boldt_WMM |
| BBS9 | BBS2 | 0.112 | 0.381 | bioplex_WMM boldt (BBS2,BBS9) boldt_WMM |
| BBS4 | TTC8 | 0.088 | 0.353 | bioplex_WMM boldt (BBS4,TTC8) boldt_WMM |
| BBS9 | LZTFL1 | 0.045 | 0.286 | bioplex (LZTFL1) bioplex_WMM boldt (BBS9,LZTFL1) boldt_WMM |
| BBS9 | BBS4 | 0.039 | 0.265 | bioplex_WMM boldt (BBS4) boldt_WMM |
| BBS5 | LZTFL1 | 0.036 | 0.264 | bioplex (LZTFL1) bioplex_WMM boldt (LZTFL1) boldt_WMM |
| BBS2 | TTC8 | 0.025 | 0.213 | bioplex_WMM boldt (TTC8) boldt_WMM |
| BBS7 | BBS10 | 0.022 | 0.208 | bioplex (BBS7) bioplex_WMM |
| BBS4 | BBS2 | 0.021 | 0.187 | bioplex_WMM boldt (BBS4) boldt_WMM |
| BBS7 | LZTFL1 | 0.013 | 0.148 | bioplex (LZTFL1) bioplex_WMM boldt (LZTFL1) boldt_WMM |
| BBS2 | LZTFL1 | 0.009 | 0.106 | bioplex (LZTFL1) bioplex_WMM boldt (LZTFL1) boldt_WMM |
| BBS1 | BBS10 | 0.008 | 0.055 | bioplex_WMM WMM_only |
| BBS4 | BBS10 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| BBS5 | BBS10 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| BBS9 | BBS10 | 0.008 | 0.024 | bioplex_WMM WMM_only |
| TTC8 | BBS10 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| BBS2 | BBS10 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| TTC8 | LZTFL1 | 0.0 | 0.009 | bioplex (LZTFL1) bioplex_WMM boldt boldt_WMM |
| BBS1 | LZTFL1 | 0.0 | 0.013 | bioplex (LZTFL1) bioplex_WMM boldt boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_04530 has an average edge precision of 0.44 which is ranked 2939 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BBS9 | HuMAP2_00695 HuMAP2_02234 HuMAP2_04530 |
| BBS1 | HuMAP2_00695 HuMAP2_02234 HuMAP2_04530 |
| BBS7 | HuMAP2_00695 HuMAP2_02234 HuMAP2_04530 HuMAP2_05079 |
| TTC8 | HuMAP2_00695 HuMAP2_02234 HuMAP2_04530 |
| BBS10 | HuMAP2_01662 HuMAP2_04530 HuMAP2_05079 |
| BBS4 | HuMAP2_00695 HuMAP2_02234 HuMAP2_04530 |
| BBS2 | HuMAP2_00695 HuMAP2_02234 HuMAP2_04530 |
| BBS5 | HuMAP2_00695 HuMAP2_02234 HuMAP2_04530 |
| LZTFL1 | HuMAP2_02234 HuMAP2_04530 HuMAP2_05368 |