hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_04531
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GET4 | Golgi to ER traffic protein 4 homolog (Conserved edge-expressed protein) (Transmembrane domain recognition complex 35 kDa subunit) (TRC35) | UniProt NCBI |
| UBL4A | Ubiquitin-like protein 4A (Ubiquitin-like protein GDX) | UniProt NCBI |
| BAG6 | Large proline-rich protein BAG6 (BAG family molecular chaperone regulator 6) (BCL2-associated athanogene 6) (BAG-6) (HLA-B-associated transcript 3) (Protein G3) (Protein Scythe) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6862 | 2.25356268047e-10 | 1.0 | GET4 BAG6 UBL4A | Bag6-Ubl4A-Trc35 Complex |
| GO:0071818 | 9.08185760231e-08 | 1.0 | GET4 BAG6 UBL4A | BAT3 complex |
| REAC:R-HSA-9609523 | 3.05725899484e-07 | 1.0 | GET4 BAG6 UBL4A | Insertion of tail-anchored proteins into the endoplasmic reticulum membrane |
| GO:0072379 | 9.08185760231e-07 | 1.0 | GET4 BAG6 UBL4A | ER membrane insertion complex |
| GO:0071816 | 1.81637152046e-06 | 1.0 | GET4 BAG6 UBL4A | tail-anchored membrane protein insertion into ER membrane |
| GO:0045048 | 3.17865016081e-06 | 1.0 | GET4 BAG6 UBL4A | protein insertion into ER membrane |
| REAC:R-HSA-9609507 | 0.000228431198544 | 1.0 | GET4 BAG6 UBL4A | Protein localization |
| GO:0007029 | 0.00137862598403 | 1.0 | GET4 BAG6 UBL4A | endoplasmic reticulum organization |
| GO:0051205 | 0.00212751596192 | 1.0 | GET4 BAG6 UBL4A | protein insertion into membrane |
| GO:0036506 | 0.00405722906526 | 0.666666666667 | GET4 BAG6 | maintenance of unfolded protein |
| GO:1904378 | 0.00405722906526 | 0.666666666667 | GET4 BAG6 | maintenance of unfolded protein involved in ERAD pathway |
| CORUM:6079 | 0.0499776345577 | 0.333333333333 | BAG6 | BAG6-HSPA2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GET4 | UBL4A | 1.0 | 0.949 | hein_WMM bioplex (GET4,UBL4A) bioplex_WMM boldt hein (GET4) boldt_WMM |
| UBL4A | BAG6 | 1.0 | 0.949 | hein_WMM bioplex (UBL4A) bioplex_WMM boldt hein (BAG6) Malo fraction boldt_WMM |
| GET4 | BAG6 | 1.0 | 0.949 | hein_WMM bioplex (GET4) bioplex_WMM boldt hein (BAG6,GET4) boldt_WMM |
Images
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Complex HuMAP2_04531 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes